However,
Can caffeine slow down cellular:
Essential
- A study on fission yeasts reveals that caffeine can prolong cell life by activating stress and repair management mechanisms.
- However, this effect depends on the presence of specific proteins, and can become harmful in the event of DNA damage. Moreover,
- These results open up new tracks on the cellular impact of caffeine, far from a simple “boost” effect. Consequently,
Behind your third espresso of the day may hide an unexpected ally of the passing time. Moreover, A new study published in the journal Microbial Cell Reveals that caffeine could influence the way our cells age. respond to stress, by activating very precise mechanisms of repair and survival.
Caffeine to prolong the life of cells? – Can caffeine slow down cellular

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Led by a team of researchers from Queen Mary University can caffeine slow down cellular of London, the experiment took place on cracks in fission (Schizosaccharomyces pombe), simple organisms but very close to the human cells used for studies on aging. Scientists have exposed these yeasts to different forms of cell stress. such as DNA damage or deprivation of nutrients, before adding caffeine to observe reactions.
The results are intriguing: even in normal conditions, caffeine has extended the lifespan of cells. Even more surprising. it did not act in a global way, but by targeting specific molecular pathways linked to the AMPK protein, a cellular energy sensor. Two key proteins, SSP1 and SSP2, play a central role here: without them, the beneficial effect of caffeine disappears. “It’s a specific tool, not a miracle remedy”summarize the researchers in a press release.
Lighting on the contradictory effects of caffeine
But beware, everything is not pink in the cup. In cells whose can caffeine slow down cellular DNA is already damaged, caffeine sometimes works. It seems to inhibit natural pause and repair systems, pushing the cells to continue to divide despite the damage. “Caffeine changes the way cells manage problems”, explain scientists. “Depending on the context, this can be useful … or harmful.”

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These results are also to be nuanced because the work has been carried out on yeasts, and the doses used largely exceed those of daily coffee. However, they offer new lighting on the complex cellular effects of caffeine. She could explain why certain clinical studies show beneficial effects of coffee, and others not …
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