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Why does champix, drug against new: Consequently,
Why does champix, drug against:
In 2021. Moreover. Meanwhile, impurities had led to the suspension of the distribution of the Tartrate de Varénicline, whose trade name is Champix. Consequently, Since then, the PFIZER laboratory has revised the formulation (the excipients have been modified) and the manufacturing process. Furthermore, It is therefore marketed again and available in pharmacies since June 17, 2025, issued on medical prescription.
“This is good news,” comments Pr Martinet, pulmonologist at the Nancy University Hospital (Meurthe-et-Moselle). Consequently, Varénicline is an effective treatment to help smokers stop. However, Its effectiveness is comparable to that of nicotine substitutes. However, Its backtrack is therefore well received. Similarly. For example, both by addictology specialists and by general practitioners, who will why does why does champix, drug against new champix, drug against again be able to prescribe it. In addition, »»
1. However, For whom? However, – Why does champix, drug against – Why does champix, drug against new
Champix. Furthermore. Nevertheless, indicated in the smoking weaning of the adult, therefore finds its place as a second intention, after the nicotine substitutes (patch, pastilles, chewing, spray, etc.).
Its prescription is interesting in patients who are highly dependent on nicotine and in check with other treatments.
The reality of patients must be taken into account. Moreover, Relapses are frequent. Nevertheless, Some had managed to stop with Varénicline, then relapsed, and found themselves without solution when the treatment disappeared. For them, this drug is a real opportunity.
2. How does this medication work? – Why does champix, drug against – Why does champix, drug against new
The why does champix, drug against new active molecule of this medication (Varénicline tartrate) acts in the same way as nicotine. fixing on the why does champix. drug against same receiver of the nervous system, and thus cancels the feeling of pleasure produced on the brain, associated with the consumption of tobacco (“partial agonist of nicotine cerebral receptors with acetylcholine”).
The need for nicotine is reduced as well as withdrawal symptoms, such as irritability or difficulty sleeping.
3. What efficiency?
The High Authority for Health (HAS) estimated in March 2025 that Varénicline (Champix 1 MG) presented an “important. medical service” in smoking cessation. in particular in people with high nicotine dependence (score in the Fagerström test higher or equal to 7).
The Champix is a twelve -week treatment issued only on prescription. A renewal of treatment is possible once if necessary.
Storage of smoking must take place between the 8th and why does champix, drug against new 14th day of treatment. If the judgment is not obtained within this period. it is not justified to continue the treatment to why does champix. drug against the end: the Varénicline is intended to accompany an effective stop, not on its own.
Can we associate the Varénicline with nicotine substitutes? “It is not absurd on the principle. ” says Pr Martinet, “but there is no scientific argument or clear pharmacological logic in favor of this combination. In the current state, it is therefore not recommended. »»
4. What are the undesirable effects?
Like any medication, the Varénicline can cause adverse effects. It must therefore be taken under medical supervision.
In terms of tolerance. the most frequently reported adverse events are nausea. insomnia, abnormal dreams and headaches, as well as “constipation and abdominal pain”, adds why does champix, drug against new Yves Martinet.
The difficulty is that some of these effects can also be linked to the stop of smoking itself. which changes sleep and digestive why does champix, drug against functioning.
Regarding the serious neuropsychiatric. cardiovascular adverse adverse effects. all of the data has not highlighted an increase in the risk of these events with Varénicline.
A possible suicidal sur-risk has long been mentioned. but the situation is now clear: “Recent studies have made it possible to raise concerns, reassures the expert. There is no identified over-risk. Vigilance remains necessary in patients with psychiatric history. Even caution with regard to driving. »»
This treatment is not recommended in pregnant or breastfeeding women, or in under 18s need specific studies. “It must also be used with caution in the event of renal failure,” recalls why does champix, drug against new Pr Martinet.
5. What dosage?
“Nausea remain the most limiting adverse effect,” says Yves Martinet. To mitigate them, progressive titration is planned from the start of treatment. We usually start why does champix, drug against with 0.5 mg once a day for three days, then 0.5 mg twice a day of day 4 a day 7 ”.
From day 8, the dosage increases to 1 mg morning and evening. The standard treatment is 12 weeks. In case of side effects, the dose can be reduced to 0.5 mg twice a day.
Varénicline can be used “safely. under medical supervision, sums up Martinet. It is a medication that allows you to quit smoking in a relatively comfortable manner. But it does not replace personal commitment: quitting smoking remains an effort. It takes a clear why does champix, drug against new decision, a suitable strategy, support. »»
And to motivate smokers. remember that the benefits of smoking stop are considerable: “A 30 -year -old person who stops smoking earns up. to ten years of life expectancy. »»
The 20 off, the Official Journal Published the price and the reimbursement rate of the drug: 27.70 euros for a box of 28 film -coated tablets dosed at 1 mg, 54.98 euros for a box of 56, with a reimbursement fixed at 65 %.
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