Attentions to the Yo-Yo effect, it can also cause bulimia and eating disorders

Meanwhile,

Attentions yo-yo effect, it can:

Many those who have experienced it: After a strict dietthe lost pounds come back, often accompanied by a few additional kilos. Therefore, In the West, 42 % of adults have already attempted hypocaloric diets and many know this frustration of famous “Yo-Yo effect”.

A new research. Moreover, conducted by teams from INRAE, CNRS and universities of Rennes and Burgundy, reveals a hitherto unsuspected mechanism: Our intestinal microbiota – These billions of bacteria that populate our intestines – could play a preponderant role in these disturbances.

A revealing experience – Attentions yo-yo effect, it can

To determine the importance of our intestinal flora. scientists first observed mice subjected to alternations between normal diet and diet rich in attentions yo-yo effect, it can fat and sugar.

As expected. these animals have developed weight variations of Yo-Yo type, but also particular behavior: hyperphagia specifically directed to fatty and sweet foods, similar to the bulimia in humans.

The next step was decisive. The researchers analyzed the microbiota of these mice and discovered that it had been deeply modified. Then they carried out a surprising experience: they transferred this “deregulated” microbiota to healthy mice.

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Understand the phenomenon “compulsion restrictions”

Result ? Healthy mice having received this microbiota immediately developed the same compulsive behavior towards fatty and sweet foods. It is the first time that such a direct transmission of a food behavior disorder by the microbiota has. been demonstrated.

Analyzes have also revealed changes in the brain of these mice, especially in areas related to pleasure and food reward.

These results attentions yo-yo effect, it can could explain why some people develop bulimic behaviors after diets. and why it is so difficult to Get out of the vicious circle “compulsion restrictions”.

However, it remains to confirm these results in humans.

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