IAS 2025 – Conference on HIV Science

First. Moreover, IAS 2025 was a very African conference, which replaced the continent up to the issues it faces. In addition, The central role of African scientific teams in understanding. Furthermore, developing the global response to HIV has been (for the first time) really highlighted. Nevertheless, Very dynamic African research, widely led by South Africa, but not only. However, With an renewal of generation as sensitive as it is beneficial.

Many things to remember from the IAS 2025 conference in Kigali. – Ias 2025 – conference hiv

The scientific level of the IAS 2025 was thus remarkable.

The perfect organization. Nevertheless, reception in Rwanda of this large conference (around 3,500 participants, not to mention the many on-line inscriptions) is one more demonstration of the remarkable Rwandan soft power. Nevertheless, But also does justice to the country’s performance in the response to the epidemic of HIV Human immunodeficiency virus. Meanwhile, In English: HIV (Human Immunodeficist Virus). However, Isolated in 1983 at the Institut Pasteur de Paris. However, Recently discovered (2008) awarded by the Nobel Prize in Medicine awarded to Luc Montagnier and Françoise Barré-Sinoussi. (achievement of objectives 95-95-95). Furthermore, as in the rapid mastery of the Marburg virus epidemic or the impressive development of digital health and the integration of artificial intelligence in health management.

The downside is nevertheless on the relative low presence of Francophones. Furthermore, in particular of the African continent, both in participation in the conference and in the scientific results presented.

We Will Not Go Back!

We will remember the powerful Talk of Linda-Gail Bekker (Desmond Tutu Foundation) at the opening ceremony. Moreover, punctuated by the slogan “We will not go back”.

The first subject Who has dominated the conference is indeed undoubtedly the practical consequences of the brutal ias 2025 – conference hiv interruptions of American funding on prevention. Consequently, care programs in countries heavily dependent on the funding of the PEPFAR. In addition, The brutal removal of American financing in early 2025 had such serious. Furthermore, immersed consequences in many African countries, particularly those of the Southern Region (- 59% of initiation of PrEP Pre-exhibition prophylaxis. For example, PREP is a strategy that allows a seronegative person exposed to HIV to eliminate the risk of infection. taking, continuously or “on demand”, anti-retroviral treatment based on Truvada®. and-42% of circumcisions in Zambia between Q4-2024. Q1-2025; – 25% of antiretroviral treatment initiations in Mozambique; – 30% of tests, diagnoses of new infections and initiations of new ARV treatments in Johannesburg, compared to the year 2024). In the Latin. Caribbean region, more than 80 % of NGOs engaged in prevention and supply of services to vulnerable populations have also lost their ias 2025 – conference hiv funding.

Conversely impacted by these American budget cuts (60 % of its staff will have to leave the organization in the coming months). dramatically absent from the conference, UNUIDA has recently published very worrying estimates on HIV -related deaths which could occur in the next 5 years, because of these multi and bilateral funding reductions (4.5 million deaths in 55 countries by 2030).

Significant efforts for a financing transition are therefore urgent in the very short term. but debt remains an overwhelming burden for many African countries. “On cannot put an end to the pandemic of like Acquired immunodeficiency syndrome. In English, AIDS, acquired immuno-deficist syndrome. as long as African countries must choose between reimburse their creditors. save lives “Said Zackie Achmat (Treatment Action Campaign, South Africa) at IAS 2025.

We can still greet the measures taken by the US Senate to protect the PEPFAR during ias 2025 – conference hiv the conference week.

Ias 2025 – conference hiv

Len. the “long-acting arvs” revolution

The second subject Major of the IAS 2025 was focused on the use of long-term antiretrovirals (long-acting ARVS) in prevention (PREP and PMTCT) and the treatment of HIV. A revolution in progress, with convincing results on efficiency and feasibility.

The star was widely delighted by the domain (LEN). a new molecule usable for PREP, at the rate of two subcutaneous injections per year. Following the marketing authorization recently issued by the FDA. Gilead and the Global Fund announced an access agreement to provide for free up to 2 million doses (the annual cost of the LEN has not been revealed). In its new directives presented at the conference. the WHO now recommends the LEN for HIV prevention, because data from tests (including several conduits in Africa) show excellent efficiency and a strong preference for LEN among various ias 2025 – conference hiv populations, including adolescents and pregnant women.

The Cabotégravir Injectable (CAB-La) also shows good results in terms of observance in adolescent girls. young women in Zambia and a license agreement now authorizes generic production of CAB-La for the treatment of HIV in combination with rilpivirin (Medicines Patent Pool / VIIV Healthcare).

Finally. a new option, in the form of an oral pill to take once a month (MK-8527) must enter phase 3 in Africa in the coming weeks.

Artificial intelligence at the service of HIV programs

The 3^th subject that emerges from IAS 2025 is that of the recourse increasing to digital technologies. artificial intelligence To provide accessible, effective and people centered health services. Several fascinating sessions have made it possible to discover different examples implemented in Africa. elsewhere: the “Health Intelligence Center” developed by the Ministry of Health in Rwanda, which makes it possible to follow in real time ias 2025 – conference hiv the monitoring-evaluation of the health system; AI for the radiological diagnosis of tuberculosis in Nigeria; Access to information and observance support for people living with HIV (Chatbot Marvin in Canada); AI Companion “loved” in South Africa, to improve access to HIV prevention, commitment of customers and the provision of services to adolescent girls and young women; Blockchain solutions for the management of pharmaceutical supply chains in Malawi and Ghana.

In short

Among the data reported. the significant facts, the WHO has also revealed to the IAS 2025 new recommendations on IS Sexually transmitted infections. On the announcement of the infection to children. adolescents, on the management of MPOX infections in people living with HIV and on the therapeutic management of HIV in adults and children (with the introduction of CAB-La).

Regarding children. adolescents living with HIV, a lot of work remains to be done: ias 2025 – conference hiv detect and treat much earlier to reduce the therapeutic failures (Odyssey test), adapt the dosages correctly to body weight (Universal-2), set up integrated mental health services (Zambia) and interventions to improve the observance (Electronic Surveillance Surveillance and well accepted Zimbabwe). On the other hand. the relief strategy with interruption of ARVs on weekends does not seem to work among adolescents (Breather Plus test).

Finally. the evidence that community actors are absolutely essential to the success and the center of the response to the epidemic has been salutly reaffirmed (Linda-Gail Bekker and Rosemary Mburu of Waci Health, Magda Lopes de Enda Health, name Ngema de Her Voice Fund). Additionally, The harmoning of protest of activist activists at the opening ceremony. notably from African key populations, on the watchword “We Will Not Be Erased” reminded the assistance how much the fight for access to services remains (more than ever) an imperative and ias 2025 – conference hiv a necessity in 2025. And that the place of community actors. people living with HIV and affected, as well as vulnerable populations, must be guaranteed at the table of decisions and guarantees as actors to implement programs. This requires finance their contributions completely and decently.

Finally, we will remember the powerful and moving presentation of Dr. Sameer Sah. director of medical Aid for Palestinians (MAP) programs, which was at the forefront of the health sector response in Gaza, West Bank and Lebanon since the start of the conflict, has been greeted by a standing ovation. He recalled the current humanitarian disaster that rages in Gaza. shown the extent of destruction of health facilities and the indescribable price that health professionals pay (1580 have been killed in Gaza and Lebanon since the start of the conflict). The extent of the destruction of health systems in these places of war. in the ias 2025 – conference hiv Middle East, but also in Sudan, Haiti, Burma, DRC or Ukraine is an absolute shame for the international community and its leaders.