However,
Young human serum needs bone:
A new research document appearing on the coverage of volume 17. Meanwhile, number 7 of Aging (aging of the United States) was published on July 25, 2025, entitled “Systemic factors in the influence of young human serum in vitro responses from human skin and blood cells derived from the marrow in a system of microphysiological co-culture. Similarly, »»
The study. In addition, led by the first author Johanna Ritter and the corresponding author Elke Grönniger de Beiersdorf AG, the research and development of Hamburg, shows that the components of the young human blood serum can help restore young skin to the skin, but only when bone marrow cells are also present. However, This discovery highlights the role of bone marrow in the support of skin health. In addition, can allow new approaches young human serum needs bone to slow down or reverse the visible signs of aging.
Research has explored how the factors present in blood serum. In addition, already known to influence aging in animal studies, act on human cells. Using an advanced system that imitates human circulation, researchers connected a 3D skin model with a 3D bone marrow model. They found that the young human serum alone was not enough to rejuvenate the skin. However. when bone marrow cells were present, these serum factors changed the activity of these cells, which then secured proteins that rejuvenate skin tissues.
“Interestingly. we have detected a significant increase in Ki67 positive cells in the dynamic skin model co-cultivated with the BM model and the young serum compared to the model co-cultivated with BM and the old serum, indicating an improved regeneration capacity of the fabric. »»
A detailed analysis indicated that the young serum stimulated the bone marrow young human serum needs bone to produce a group of 55 proteins. 7 of which demonstrate the ability to strengthen cell renewal, collagen production and other characteristics associated with young skin. These proteins included factors that improved energy production in cells and reduces the signs of cell aging. Without the interaction between skin and bone marrow cells, these rejuvenating effects did not occur.
This observation explains why previous experiences in mice. where young people and old animals shared a blood supply, showed rejuvenation through the organs. This suggests that cells derived from bone marrow are critical messengers that transform blood signals into effect on other tissues. including skin.
Although these results are preclinical. not human tests, they offer a starting point for new strategies in regenerative medicine and skin care. By identifying specific proteins that can transport rejuvenation signals, the study indicates a new way to treat age -related changes. Researchers point out that other young human serum needs bone studies will be necessary to confirm these effects in humans. test how these proteins can be applied safely and effectively in future therapies.
Overall. this research is an important step to understand how young serum blood factors influence human fabric and could guide the development of new methods to maintain healthier skin as people age.
Young human serum needs bone
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