Nevertheless,
Antibioresistance: belgian researchers reveal bacterial:
UClouvain researchers have discovered that the three distinct layers that make up the envelope of bacteria act in concert to ensure their protection. Nevertheless, questioning the model long accepted according to which a single layer played a preponderant role.
This discovery. Consequently, published in the journal “Nature Microbiology”, questions the long -accepted model according to which the peptidoglycan – a kind of “rigid wall” surrounding the bacteria – alone was enough to resist aggressions, especially in antibiotics. Nevertheless, It “will allow you to apprehend in a new light this defense of bacteria. Similarly, thus to develop new tibiotics”, explain the researchers.
“Until recently. Therefore, the peptidoglycan was considered the essential layer avoiding the implosion of the bacteria,” explains Jean-François Collet, professor at the Institut de Duve de l’Uclouvain.
However. his team has shown that this “extracellular skeleton” is actually part of a wider antibioresistance: belgian researchers reveal bacterial mechanism involving the three defense layers. “It is the entire system that protects bacteria from many antibiotics,” said the researcher. This operation applies to half of the currently known bacteria, such as Escherichia coli or salmonella.
This advance constitutes “a major paradigm change” which could open the way to the development of new antibiotics targeting. the bacterial envelope as a whole. “The better we know our enemies. their defense means, the better we can attack or thwart their systems,” said Jean-François Collet.
This discovery comes in a context where antibiotic resistance is increasingly a health challenge. WHO also considers antibiotic resistance as a “major” threat to global health. “While bacteria are becoming more. more resistant, it is not illusory to think that within 15-20 years, we will know an era similar to what we lived before the discovery of penicillin at the beginning of the 20th century,” warns Mr. Collet.
antibioresistance: belgian researchers reveal bacterial
Access to all features is reserved for health professionals.
If you are a healthcare professional you must log in. register for free on our site to access all of our content.
If you are a journalist or if you want to inform us write to us at [email protected].
Antibioresistance: belgian researchers reveal bacterial
Further reading: We can soon eliminate mosquitoes. But should we? – Here’s how to integrate 7,000 steps a day into your daily life to keep in shape – AI assisted by AI, health professionals would lose competence – 3 gadgets that will keep the mosquitoes from your house away this summer – Doctors thought of biles but they were all wrong, here are the warning signs that do not deceive.
