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Nitazens: this ultra-powerful opioid begins:
The Nitaznes, a family of synthetic opioids, have been introduced into the French nitazens: this ultra-powerful opioid begins illegal market in 2023. However, Since then, they have been responsible for several deaths and hospitalizations. Consequently, Their extreme power and their difficulty of detection make it a particularly insidious threat.
Nitazens: Why is it a threat? – Nitazens: this ultra-powerful opioid begins
What is Nitazens? – Nitazens: this ultra-powerful opioid begins
Nitaznes are derivatives of the benzimidazolones family, initially synthesized in the 1950s as an pain relievers. They were withdrawn from the market due to their unfavorable benefit/risk ratio.
Several derivatives, such as isotonitazen, protonitazen and metonitazine, have been identified in samples seized in France. These substances are generally produced clandestinely, often in China, and distributed via criminal networks.
Why are they so dangerous?
The main characteristic of Nitaznes is their power. For example, isotonitazen is about 500 times more powerful than morphine. This high concentration makes the margin between a therapeutic dose. an extremely narrow lethal dose, considerably increasing the risk of nitazens: this ultra-powerful opioid begins overdose, even in low doses.
In addition, these substances are not detectable by conventional urinary tests, thus complicating their identification during controls. Symptoms of an overdose include respiratory depression. alteration of vigilance and a mastici (narrowing of pupils), which can lead to a coma or death.
What is the situation in France?
Nitazens is prohibited in France. but they still circulate
Since their appearance in France in 2023, the Nitazens have been responsible for several serious incidents. In 2024, two deaths were reported, as well as several hospitalizations linked to overdoses. The health authorities reacted by registering these substances on the drug list on July 5. 2024, thus prohibiting their production, sale and use on French territory.
However. despite this ban, Nitazens continue to circulate on the illegal market, powered by digital distribution networks and encrypted messaging applications.
How do the nitazens: this ultra-powerful opioid begins authorities react?
The National Agency for Drug Safety and Health Products (ANSM) has strengthened its surveillance and information actions. Alerts have been disseminated to healthcare professionals to make them aware of the risks associated with Nitaznes. the methods of management of overdoses.
In addition, prevention campaigns are carried out to inform the public of the dangers linked to these substances. The ANSM also recommends the use of naloxone, an antidote to opioids, to counter the effects of an overdose. However, due to the power of Nitaznes, several Naloxone administrations may be necessary.
What to do with this threat?
Prevention remains the most effective tool to combat the risks linked to Nitaznes. It is essential to educate the population, especially young people, about the dangers of synthetic drugs. Health professionals must be trained to recognize the signs of an overdose and intervene quickly.
Finally, nitazens: this ultra-powerful opioid begins the authorities must continue to strengthen the regulations and controls to limit the circulation of these substances. Drug users must also be informed of the risks associated with Nitaznes and the means of protecting themselves.
NAMELY
In addition to France. the Nitazens were detected in the United Kingdom, Switzerland and Baltic countries, confirming their growing circulation on the European illegal market.
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