A new study confirms the cardiovascular safety of COVVI-19 vaccines

The incidence of heart attacks and brain vascular accidents was lower after COVVI-19 vaccination than before or without vaccination, according to a new study involving almost the entire adult population of England.

The study, published today in Nature communicationshas shown that the incidence of arterial thromboses, such as heart attacks and strokes, was up to 10% lower in the 13 to 24 weeks after the first dose of a COVVI-19 vaccine. After a second dose, the incidence was up to 27% lower after receiving the Astrazeneca vaccine and up to 20% lower after the Pfizer / Biotech vaccine.

The incidence of current venous thrombotic events – mainly pulmonary embolism and deep venous thrombosis of the lower limbs – has followed a similar diagram.

Research by the universities of Cambridge, Bristol and Edinburgh and activated by the British Data Science Center of the British Heart Foundation (BHF) in Health Data Research UK analyzed health files from 46 million adults in England between December 8, 2020 and January 23, 2022. cardiovascular after vaccination with incidence before or without vaccination, during the first two years of vaccination.

The Co-Prime Author, Dr. Samantha IP, research partner in the Department of Public Health and Primary Care, University of Cambridge, said: “We have studied vaccines and cardiovascular Covid-19 diseases in nearly 46 million adults in England and have found a similar or lower incidence of common cardiovascular disease, such as heart attacks and strokes, after each vaccination or without vaccination. global.«

Previous research has revealed that the incidence of rare cardiovascular complications is higher after certain COVVI-19 vaccines. For example, the incidence of myocarditis and pericarditis was reported after mRNA vaccines such as the PFIZER / Biotech vaccine, and thrombotic thrombocytopenia induced by vaccines based on adenovirus such as the astrazeneca vaccine. This study supports these results, but above all, it has not identified new unwanted cardiovascular conditions associated with COVVI-19 vaccination and offers additional comfort that the advantages of vaccination prevail over the risk.

The incidence of cardiovascular disease is higher after COVID-19, especially in serious cases. This may explain why the incidence of heart attacks and strokes is lower in vaccinated people compared to non -vaccinated persons, but other explanations go beyond this study.

The deployment of the COVVI-19 vaccination program started in the United Kingdom strongly, with more than 90% of the population over 12 years old, with at least one dose by January 2022.

This study on the level of England provides patients with the comfort of cardiovascular safety of doses of first, second and recall of COVVI-19 vaccines. He demonstrates that the advantages of the doses of second and recall, with fewer common cardiovascular events include heart attacks and strokes after vaccination, prevail over very rare cardiovascular complications. “”

Professor William Whiteley, associate director at the BHF Data Science Center and professor of neurology and epidemiology at the University of Edinburgh

The research team used data related to disintegration of general practitioners, hospital admissions and death files, analyzed in a secure data environment provided by the NHS England.

The co-author of the co-author, Dr. Venexia Walker, researcher at the University of Bristol, said: ” Given the critical role of COVVI-19 vaccines in the protection of people of COVID-19, it is important that we continue to study the advantages and risks associated with them. The availability of data on the population scale has enabled us to study different combinations of COVVI-19 vaccines and to consider rare cardiovascular complications. This would not have been possible without the very large data to which we have the privilege of accessing and our cross -school collaborations.«

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