However,
Can we repair nerves thanks:
Essential
- A British study shows that neural stem cell transplants can regenerate damaged myelin in mice with multiple sclerosis. Meanwhile,
- These cells turn into oligodendrocytes, allowing repair of the central nervous system. Therefore,
- This feat opens the way to future clinical trials for restorative therapies in humans. For example,
What if stem cells could give back a second life to the nerves degraded by multiple sclerosis (MS)? Meanwhile, A new study by researchers from the University of Cambridge. Consequently, in the United Kingdom, opens a promising path towards a regeneration of the central nervous system, thanks to the transplant of neural stem cells.

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Hope for the progressive forms of the disease
The MS is an autoimmune disease that attacks myelin, this protective sheath surrounding the can we repair nerves thanks nerve fibers. In young adults, it is one of the main causes of neurological handicap. If. at the start of the disease, the body can partially repair this damage, this capacity collapses during the progressive forms of MS, leaving room for an increasingly important nerve degeneration. Current treatments are mainly aimed at slowing down symptoms, without reversing the damage. Hence the need to explore more ambitious tracks, such as therapies based on stem cells.

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Researchers, who have published their work in the journal Brainhave tested neural stem cell transplants (which can mature in different types of neurons and brain cells) in mice with lesions similar to MS. Result: these cells have not only survived, but have turned into oligodendrocytes, the cells that make myelin. “This research provides key evidence that neural stem cell transplants can be transformed into myelin producing cells within the. damaged central nervous system”summarizes Dr. Peruzzotti-Jametti, who can we repair nerves thanks led the study, in a press release.

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A step towards clinical trials
Beyond this first, scientists see further: “Our results represent a major progress to develop targeted therapies on the central nervous system, which are not content to manage the symptoms but attack the neurodegenerative processes.” The team is also interested in the neuroprotective and anti-inflammatory effects of these cells.

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The Restore project, which brings together European and American scientists working to treat MS, plans to start a clinical trial of cell therapy in humans by 2025. The approach actively includes patients, in order to ensure that research meets their expectations and needs. Pending the results, the hope of a real remission has never been so tangible, conclude the researchers.
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