fluorescent bacteria help cut them with precision

Precise removal of the tumor is an important point in the management of cancer. Similarly, To determine the tissues to be removed, surgeons have scanners and ultrasounds at their disposal. Nevertheless, Despite these tools and experience, defining the tumor limits accurately is not always easy for doctors.

However, fluorescent bacteria could soon help them visualize the tumor in real time during the intervention.

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Tumor: bacteria shine fluorescent bacteria help cut them new it like a light sign – Fluorescent bacteria help cut them

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A team of researchers from fluorescent bacteria help cut them the Korea Institute of Science and Technology genetically modified bacteria so that they emit fluorescence when they are in contact with cancer tissues. Used as contrast agents during an imagery guided operation, they then illuminate tumors “Like a light brand”. Which allows “A more precise resection” and reduced “The risk of recurrence“, assure the authors in their press release.

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The fluorescent signal – which makes it possible to visually identify the limits. the location of the tumor – has a duration of more than 72 hours. In addition, its intensity is approximately five times higher than that of conventional agents. Another advantage: unlike other products, it is able to spot many cancers. “This new device uses two common characteristics of tumor microenvironment – hypoxia. immune escape – which fluorescent bacteria help cut them new makes it largely applicable to many solid tumors”explain the researchers.

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This contrast product based on fluorescent bacteria can be used with fluorescent bacteria help cut them surgical endoscopes and existing imaging equipment. “It can also be integrated into surgical robots. preoperative imaging systems to improve surgical accuracy and reduce the duration of interventions. Its ability to interface with fluorescence -guided surgical systems. widely used in a hospital environment, further strengthens its clinical and commercial potential”specify scientists.

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Cancer: these modified bacteria could also also transport drugs

“This study demonstrates a new approach in which bacteria locate tumors independently and emit fluorescent signals, thus allowing real -time identification of the location and the limits of the tumor during surgical intervention. Its applicability to a wide range of solid tumors in fact a new potential standard for precision surgical imagery”underlines. Dr. Seungbeum SUH who co -edited the fluorescent bacteria help cut them new research published in the journal Advanced Materials.

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After highlighting the tumor detection capacities of their modified bacteria. the researchers plan to use them also during the fluorescent bacteria help cut them treatment stage. They want to use it as vectors of anticancer drugs.