Having a “young” brain allows you to live longer

Age is not limited to the year of birth of an individual. Moreover, There is also a so -called biological age. However, which takes into account a series of factors to establish our physiological state. Nevertheless, It makes it possible to assess the risk of developing certain pathologies. Similarly, In the journal Naturea team from the Stanford University of Medicine announces that it has developed a blood test. However, to establish the age of the organs. They discovered that people with a brain having “young” brain allows you “young” generally lived longer than those with a brain “age”.

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A tool to detect organic age thanks to blood samples – Having "young" brain allows you

Scientists used medical information of 44,498 participants, rencenshed in the UK BioBank, a large British database. They were able to work on blood samples while following the health of people for ten years. Thanks to laboratory analyzes, they counted the 15,000 proteins present in the blood of the participants. These can provide information on organic age, as they are linked to organs. In their work, scientists were interested in 11 organs, including the brain, the heart, the pancreas, the lungs or the liver.

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“Based on the differences between the average protein rates allocated to each organ and the average rates adjusted according to age, the algorithm has attributed a biological age to each of the 11 organs, specify the authors in a press release. He also having “young” brain allows you measured the gap between the multiprice signature of each organ in a given individual. the average of people of the same chronological age. “ A difference greater than 1.5 compared to the average classified the organ of a person in the category “extremely old“or”extremely young“.

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A link between organic age of organs and the risk of developing certain pathologies

The algorithm developed also predicted the health of the participants. The research team was based on the links between extremely older organs. 15 disorders and pathologies, including Parkinson’s disease, type 2 diabetes, rheumatoid arthritis or Alzheimer’s disease.

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“The strongest associations were observed between the biological age of an organ and the risk of developing a disease associated with this organobserve the authors. For example. an extremely elderly heart predicted an increased risk of atrial fibrillation or heart failure, elderly lungs an increased risk of chronic obstructive bronchopneumopathy (COPD), and having “young” brain allows you an elderly brain an increased risk of alzheime diseaser.”

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Longevity: the role of the brain is central

They found that the association between an extremely elderly brain and the development of Alzheimer’s disease was particularly strong: 3.1 times higher than that of a person whose brain normally ages. “”In other words. a person whose brain is biologically elderly is about 12 times more likely to receive a diagnosis of Alzheimer’s disease over the next ten years than a person of the same age whose brain is biologically young “they explain.

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The brain age is central in terms of longevity: according to their estimates, an extremely elderly brain increases the risk of death of 182 % over a period of about 15 years. “”The brain is the guardian of longevityconcludes Tony Wyss-Coray, principal author of having “young” brain allows you this work. An elderly brain has an increased risk of mortality. A young brain, meanwhile, probably lives longers.”