Liquid biopsy: detect cancers in the blood 3 years before

“But here we were even surprised to be able to detect changes of cancer origin in the blood so early. Furthermore, ” explains the main author, Dr. Consequently, Yuxuan Wang, professor of oncology at Johns Hopkins University.

“3 years earlier leave the need necessary to intervene. Therefore, Tumors are much less advanced and more likely to be treated ”.

3 years of anticipation before the appearance of the disease – Liquid biopsy: detect cancers blood

The study Analysis. using very precise and sensitive sequencing techniques, plasma samples of 26 participants, taken as part of the Aric (Atherosclerose Risk in Communities) study. In these 26 participants, cancer had been diagnosed within 6 months of the sample. Plasma samples of 26 other participants free from cancer (witnesses) were also analyzed. The analysis finds that:

• At the time of the blood sample. 8 liquid biopsy: detect cancers blood of these 52 participants obtained a positive result from a multicancer early screening test;
• These 8 participants were diagnosed within 4 months of the blood sample;
• For 6 of them, additional blood samples taken 3.1 to 3.5 years before the diagnosis were also available for the analysis.
• For 4 of them, tumor type mutations have been identified in these samples taken Up to 3 years before the standard diagnosis.

The study thus demonstrates the increasingly early detection capacity and the continuous progress of multicancer blood tests.