In addition,
Study reveals turning point when:
- Previous studies show that human aging does not necessarily occur at the same rate throughout our lives. However. However,
- There is still a lot to discover on the aging process, especially with regard to its impact on body organs.
- A new study revealed that by focusing on protein changes related to aging in the body. Similarly, there is study reveals turning point when an acceleration of aging of organs and tissues around the age of 50. Nevertheless,
- And among these proteins. Nevertheless. However, scientists have found that the expressions of 48 of them are linked to diseases increased with age, such as cardiovascular and hepatic diseases. Meanwhile. Moreover,
Although we can try to slow it down, human aging is something that we cannot study reveals turning point when currently prevent from happening. However, previous studies show that aging does not necessarily occur at the same rate throughout our lives. Similarly,
Instead, there are certain ages when a person’s body may feel an explosion of aging. Meanwhile, Previous studies show that the body can undergo rapid aging 44 and 60 years old.
And there is still a lot to discover on the aging process. For example, especially with regard to its impact on body study reveals turning point when organs. Meanwhile,
“Aging. However. Therefore, as a systemic and degenerative process which covers several organs and biological strata, remains one of the deepest unresolved questions in life sciences,” said Guang-Hui Liu, PHD, researcher in regenerative medicine at the Chinese Academy of Sciences, Medical news today.
“Throughout the prolonged human life. Consequently, two fundamental questions persist: do all organ systems study reveals turning point when adhere to a unified aging rate? Consequently, Does a molecular spatio-temporal center exist which orchestrate senescence on the scale of the organism? Similarly, Despite their centrality to understand the essence of age.
Liu is the corresponding author of a new study recently published in the journal Cell This revealed. However, that by focusing on protein changes linked to aging in the body. Therefore. Furthermore, they can obtain a clearer image of how body organs and tissues age over time, study reveals turning point when including aging acceleration around the age of 50. For example,
And among these proteins. In addition. Consequently, scientists found that the expressions of 48 of them were linked to diseases – such as cardiovascular disease and fatty liver disease – have increased with age. Consequently,
Study reveals turning point when
Creation of an aging “Atlas”
For study reveals turning point when this study. Furthermore, the researchers analyzed 516 samples of 13 types of human tissue collected from 76 organ donors aged 14 to 68 who died of traumatic brain lesions.
The tissue samples included cardiovascular, digestive, respiratory, endocrinian and musculoskeletal samples, as well as samples of immune, skin and blood.
Then. the researchers documented the types of protein found in organ. tissue samples, study reveals turning point when allowing them to create what Liu called “a proteomic aging atlas” which extends over 50 years of human life.
“Covering seven physiological systems. thirteen pivot tissues. the Atlas presents a panoramic and dynamic portrait of organizational aging from a protein -centered perspective,” said Liu. “The more than 20. 000 proteins coded by the genome serve the structural foundation of cells. Their dynamic networks orchestrate exquisite physiological homeostasis and act as the main executors of almost all biological processes. Additionally, study reveals turning point when ”
“Consequently. the systematic traffic of a panoramic atlas at the scale of the life of the proteomic dynamic. the dissection of the reprogramming rules of the protein networks to scales at the level of the organ and the system are essential to identify with precision the main engines of aging and to establish precise intervention targets,” he added.
study reveals turning point when
The aging of the body accelerates around 50 years
At the conclusion of the study. the researchers found that the greatest aging changes in the organs and tissues of the body seem to occur around 50 years.
The critical aging window
“The 45 to 55 year olds are identified as. a historical inflection point: most organ proteome undergoes a” molecular cascade storm “. with proteins expressed differentially study reveals turning point when exploding in an explosive manner. marking this interval as the critical biological transition window for systemic and multi-organization aging.”
– Guang-Hui Liu. PhD
“In particular. the aortic proteo is most radically reshaped; Its secretory and the circulating plasma proteo evolve in a tight concordance, indicating that the secreted factors associated with senescence study reveals turning point when (Senokines) can serve as a hub mechanism diffusing aging signals throughout the body, “said Liu.
In addition. Liu. his team found that the expressions of 48 proteins related to diseases, including cardiovascular disease, liver disease, tissue fibrosis and liver tumors have increased with age.
“Aging of organs is the essence of chronic human disease. Each geriatric disease is only a specific manifestation of this underlying organ aging, ”added Liu.
Aging causes biochemical changes in the body
Mnt had the opportunity to speak with Cheng-Han Chen. MD, certified interventional cardiologist and medical director of the HEArt structural program at the Memorialcare Saddleback Medical Center in Laguna Hills, California, about this study.
“This study revealed that protein changes in the body associated study reveals turning point when with aging seem to accelerate roughly around the age of 50. depending on the type of body tissue. It is an interesting discovery that helps us to better understand the types of biochemical changes that underlie aging. potentially provide targets for therapy at different stages of someone’s life. ”
– Cheng-Han Chen, MD
“Science begins to only understand the biological mechanisms involved in aging,” said Chen. “Studies like this help us to identify the basis of normal aging.. in turn give an overview of how normal biology differences lead to diseases such as study reveals turning point when cardiovascular disease and liver disease.
“Future research should try to develop these results in more diverse demographic groups. in other important organs such as the brain and the kidneys,” he added.
Transform study reveals turning point when reactive medicine to proactive
Mnt He also spoke to Manisha Parulekar. MD, chief of the geriatric division at Hackensack University Medical Center in New Jersey, about this research.
How aging affects the whole body
“The idea that our cells lose the ability to maintain a healthy. functional proteo (the protein collection) is a cornerstone of modern aging theory. The accumulation of poorly folded protein. as amyloidsis the classic example, the best known in neurodegenerative diseases such as Alzheimer’s disease. The conclusion of this study study reveals turning point when of a generalized amyloid accumulation in many tissues confirms. that it is not only. a specific problem of the brain but a systemic characteristic of aging. »»
– Manisha Parulekar. MD
“This research aims to transform the medicine of a reactive model. focused on the disease into a study reveals turning point when proactive and health-focused model,” she continued. “By understanding the what. the moment of aging. we can develop tools to compress morbidity – allowing people to live not only, but a healthier and more dynamic life.”
“A longitudinal study. following the same people during the decades. will be useful,” added Parulekar when asked what she would like to see as the next steps for this research. “This would follow their personal proteomic changes over time. which would allow us to study the genetic differences. lifestyle between people and additional confirmation of the” inflection point of the study reveals turning point when age of 50 “.”
Dr Stéphane study reveals turning point when Cohen
Dr. Cohen writes for 30 years and is a world renowned expert in the field of medicine and well-being. Acclaimed speaker, Dr. Stéphane Cohen has given more than 100 conferences in Europe as well as numerous conferences abroad to various audiences. including in the United States.
No result
View All Result
Study reveals turning point when
Study reveals turning point when
Further reading: It was cancer, their diagnostic error was fatal to him – Experts explain how to avoid 60 % of cases – Pays de la Loire: the bat, a small animal that can transmit the rage virus, “do not touch it!” – Amibiasis and other intestinal parasitoses – The two X women’s chromosomes, suspected of being the cause of certain diseases.
Further reading: Chikungunya and dengue: 21 Aboriginal transmission episodes identified in France | The doctor’s daily life | Specialties – A new scientific breakthrough to treat chronic pain – Virtual reality could lead to our body to fight infections, according to a study – 27 cases of dengue and chikungunya identified since May 1 in PACA: ARS is strengthening the fight against the Tigre mosquito – The discovery of the UCSF points to new strategies for the treatment of Alzheimer’s.