Bulletin n ° 7 – July 2025

The main French vaccinology congress (JPIPA). Consequently, coordinated by Infovac, will take place on October 11, 2025 at the Maison de la Chimie (Paris). Meanwhile, If you want to register, Click herethe Infovac team awaits you.

1. Moreover, On the side of the authorities

The Vaccination against chikungunya Definitely knows a rapid succession of twists. However, turns, sometimes difficult to follow. Therefore, Due to the intensity of the epidemic in Reunion. Similarly, the health authorities had first issued, in a Provisional opinion, a preferential vaccination recommendation for the elderly – The most at risk of serious forms – with the alive attenuated vaccine DISCIFIED (Valneva). Similarly, Like all living vaccines, it is contraindicated in immunocompromised people and pregnant women. In addition, A few weeks later. However, due to the occurrence of serious bulletin n ° 7 – side effects, including two deaths in vaccinated elderly, Vaccination has been suspended in those over 65. Meanwhile, At the end of May 2025. Similarly, a new vaccine, Vimkya® (Bavarian Nordic), composed of Pseudo-viral parties (same principle as for HPV vaccines), was marketed. Furthermore, Although no official recommendation has been made to date, it could be safer in elderly and immunocompromised subjects. Therefore, It is currently not reimbursed and its price exceeds € 165. Moreover, In June 2025. Nevertheless, The High Public Health Council published recommendations for travelers On the respective indications of each of the two vaccines. However. these recommendations partly lost their relevance after lifting, by the European Medicines Agency, On July 14, temporary restrictions on the use of IXCHIQ® in those over 65. The agency nevertheless recalls that the vaccine should only be administered in the presence of a significant risk of serious infection. and emphasizes that the bulletin n ° 7 – serious adverse effects have been reported mainly in elderly patients and presenting comorbidities. She insists on the benefit for the elderly at risk of severe form.

LakeAGAND OF HPV and MENINGOCOQUECE ACYW infections will take place between January and June. Two doses will be administered for HPVa dose unique for the Acwy meningococcal vaccine. Co-administration is possible and even desirable during the same vaccine session. The consent of both parents remains required. Vaccinations will be carried out by medical teams designated by the ARS.

The High Authority for Health recommended the conjugated vaccine 21-Valent Capvaxive® (MSD). Like the Prevenar 20® (Pfizer), in the strategy against invasive pneumococcal infections in the adult.

2. For your information

Anti-vaccine movements are experiencing renewed vigor Since the election of Donald Trump. the appointment of a notorious opponent of vaccination at the head of the Ministry of Health in the US. Several recent publications continue bulletin n ° 7 – to highlight the efficiency and tolerance of vaccines.

– a development published on June 26. 2025 in the New England Journal of Medicine Confirms both the severity of measles, the efficiency and safety of available vaccines, as well as the central role in the insufficiency of vaccination coverage in the occurrence of current epidemics. Reading this article, which offers an updated synthesis on measles, is highly recommended. In these holiday periods. we remind you of the usefulness of ROR vaccination between 6 and 12 months for certain countries, and the need to then make the 2 doses, at 12 and 16-18 months. All children who have received their 1^era Dose before 12 months then to receive 2 doses.

– In Denmark. a large study of a national cohort relating to more than a million children has found No risk increases of autoimmune, atopic, allergic diseases, or neurodevelopment disorders linked to bulletin n ° 7 – early exposure to aluminum vaccines. This publication further strengthens the consensual position of health authorities and learned, national and international companies, expressed for years.

– In France. the ANSM pharmacovigilance report on the vaccination campaign in schools last year confirms the security of the Gardasil 9®.

3. In response to your questions.

I saw a 6 -month -old child who had a florid chickenpox with a high fever and a very extensive eruption. Should I offer him vaccination after the age of a year? YES ! Varicels made for 1 year, especially before 6 months, are less immunogenic. Several studies have shown that children who have had an early chickenpox have an increased risk of making a 2^th chickenpox. an early zona. This is linked on the one hand to the presence of maternal antibodies which can neutralize the virus. on the other hand to the immune to infants. bulletin n ° 7 – THE vaccine can serve as «booster», Reinforcing humoral and cellular immune memory. As a result. in Canada, in the United States, Switzerland, we do not take it into it and 2 doses of vaccines are recommended.

J‘I have prescribed an immune balance sheet for a 14 -year -old teenager with recurrent febrile orl episodes for several months. The weight dosage of immunoglobulins reveals an isolated IGA deficit (<0.05 g/l). Should we make vaccination serologies, and if so, which ones? Non. The selective IGA deficit is the most common primary immune deficit. Although it can be accompanied by infections of recurrent mucous membranes. in particular ENT, it does not alter the response to injectable vaccines. It is therefore not necessary to control vaccine serologies. On the other hand. it is reasonable to offer a Annual antigrippal vaccinationas well as a Conjugated antipneumococcal vaccine dose (Prevenar 20® or Capvaxive®), in an attempt bulletin n ° 7 – to limit the risk of repeated respiratory infections.

Robert Cohen. Pierre Bakhache, Georges Thiebault, Catherine Weil-Olivier, Didier Pinquier, Sabelle Hau, Joël Gaudélus, Pierre Bégué, Marie-Aliette Dommergues, Véronique Dufour, Hervé Haas, Cécile Janssen, Odile Launay, Maeva Lefebvre, Anne-Sophie Romain, Franck Thollot, François Vie.

Trelogies an PDF