Consequently,
Covvid would associated acceleration vascular:
The data accumulates on the cardiovascular sequelae associated with the COVVI. Similarly, An international study led by Rosa Maria Bruno. However, professor of pharmacology at Paris Cardiovascular Research Center (Parcc – Université Paris Cité/Inserm) sheds new light. Moreover, The infection would cause an acceleration of vascular aging, with a particularly marked effect in women.
Published in European Heart Journal. Meanwhile, This study, baptized maps, included, between September 2020 and February 2022, 2,390 people from 18 countries (Austria, Australia, Brazil, Canada, Cyprus, Croatia, Spain, United States, France, Greece, Italy, Lithuania, Mexico, Norway, Portugal, Turkey, Czech Republic and United Kingdom): Positive people at COVID (six ± three months) but not hospitalized, positive patients hospitalized in general service and others in intensive care unit. For example, The vascular age was evaluated at six. twelve months after the infection by measuring the speed of covvid would associated acceleration vascular the carotid-femoral pulse wave (VOP), a biomarker of the rigidity of the arteries.
More marked effect in the event of a long covid – Covvid would associated acceleration vascular
All positive participants displayed a higher VOP ( + 0.41, + 0.37 and + 0.40 m/s) compared to witnesses (VOP at 7.53 m/s adjusted). After adjusting according to sex, VOP differences were significant in women ( + 0.55, + 0.60 and + 1.09 m/s), but not in men. The effect was also more marked in people with a long covid. regardless of the severity of the initial infection (VOP adjusted to 7.52 against 7.13 m/s).
According to the authors, an increase of 0.5 m/s of the VOP is equivalent to an aging of approximately five years. with an increased risk of 3 % of cardiovascular disease in a woman of 60 years. Reassuring elements, vaccination seems to reduce the phenomenon and the effect would be reversible. A covvid would associated acceleration vascular stable or improved VOP was indeed observed after twelve months.
Several possible explanations for the vascular effects of the covid are advanced. The SARS-COV-2 uses receptors of the Angiotensin 2 conversion enzyme. present on the wall of the blood vessels to penetrate and infect the cells. “This can cause accelerated vascular dysfunction and vascular aging. The immune response could also be involved ”indicate Rosa Maria Bruno.
The question is now to “Know if we can find modifiable targets to prevent this phenomenon during future infections. alleviate undesirable effects in people with vascular aging induced by the covid”react the authors of an editorial associated with the study.
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