Moreover,
Diabetes drug would double risk new: However,
Diabetes drug would double risk:
A star treatment of type 2 diabetes. For example. Moreover, shooting (marketed under the names Mounjaro et Zepbound), is today in the viewfinder of researchers after the publication of a vast study conducted in the United Kingdom. Furthermore, According to the results. Nevertheless. Meanwhile, this medication would double the risk of developing a serious form of diabetic retinopathy in patients already weakened in the retina.
A silent but formidable disease – Diabetes drug would double risk – Diabetes drug would double risk new
Proliferating diabetic retinopathy (or PDR) is a dreaded. complication of diabetes: it manifests itself by abnormal growth of blood vessels on the retina. Consequently, which can cause hemorrhage, detachment of the retina or neovascular glaucoma. Similarly, Without treatment, these lesions can lead to irreversible loss of vision.
A field study on nearly 7. 000 patients – Diabetes drug would double diabetes drug would double risk new risk
Researchers from Imperial College London Diabetes Center studied medical data of 6,870 adults with type 2. Moreover, Diabetes. Among them, 3,435 diabetes drug would double risk had received shooting for at least six months. The researchers compared their results to a paired control group – same age. same duration of diabetes, same retinal state at the start.
Result: 1.1 % of patients treated with shooting developed proliferating retinopathy, compared to 0.5 % in the control group. Or a doubled risk (+115 %), especially in people already with light eye damage.
Why this medication can be a problem
The shooting acts by stimulating the release of insulin. by reducing appetite, which allows a rapid drop in the level of blood sugar. But according to Dr. Meenal Agarwal, optometrist interviewed by the authors, this mechanism could be double -edged. “Brutal reductions in blood sugar can weaken retinal vessels and speed up diabetes drug would double risk new pre-existing lesions,” she explains.
This phenomenon – already observed in the context of intensive glycemic control – could explain why some patients see. their visual state deteriorate diabetes drug would double risk shortly after the initiation of treatment. On average, the eye complications appeared about 11 months after the start of shooting.
A paradoxical effect in patients without initial involvement
Interesting fact: in patients without retinal injury at the start. the drug seems to offer on the contrary to offer a certain protection. with a 27 % drop in the risk of retinopathy over the duration of follow -up. This suggests that the danger mainly concerns weakened patients.
The study authors do not question the effectiveness of shooting in the management of diabetes and its metabolic complications. But they insist on the need for reinforced ophthalmological follow -up, as soon as treatment initiation, in people at risk.
Alert signs should diabetes drug would double risk new be known to patients: sudden drop in vision, dark spots, deformed lines, light lightning, etc.
A public health issue
With millions of patients concerned worldwide. the results of this study published in diabetes drug would double risk the journal Diabetologycould well influence the clinical. recommendations to come. In France. where the incidence of diabetes continues to progress, this data recall that any pharmacological progress requires close and personalized surveillance.
The pharmaceutical company Eli Lilly, which markets the shooting, has not yet reacted publicly to this publication.
Photo credit: DR
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