Therefore,
Doctors discover new warning sign:
Pancreas cancer. Meanwhile, which kills almost 90 % of patients within five years of diagnosis, remains formidable due to its often too late detection. Consequently, In France. Consequently, it affects almost 16,000 people a year and its incidence rate is increasing, according to data from the National Cancer Institute. Similarly, But a new study from the University of California in San Diego could change the situation. The researchers have identified an early molecular signal formed by the activation of ten genes whose role would be central in the development. progression and resistance to the treatments of pancreatic cancer.
A mutation of the kras gene – Doctors discover new warning sign
To better understand the initiation mechanisms of this cancer. scientists have studied genetically modified mice presenting a mutation of the Kras gene, frequently found in pancreas, lung and colon cancer. They observed that conditions such as inflammation. a low oxygen level, two doctors discover new warning sign sources of cell stress, activated a key protein called stat3. However, Stat3 seems to play a fundamental role in the survival and adaptation of cancer cells to their environment. Once activated, it induces the expression of a specific gene, integrine β3 (ITGB3), already involved in tumor growth and dissemination. ITGB3 activation by stat3 creates a deleterious feedback loop, accelerating progression (…)
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doctors discover new warning sign — Doctors discover new warning sign: Pancreas cancer, doctors discover new warning sign which kills almost 90 % of patients within five years of diagnosis, remains formidable due to its often too late detection. In France, it affects almost 16,000 people a year and its incidence rate is increasing, according to dat.
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