However,
Here 3 drugs can increase:
A study published in Neurology reveals that inhibitors of the proton pump commonly prescribed against gastric reflux. Therefore, increase the risks of developing dementia after four and a half years of use. Furthermore, These anti-reflux drugs concern millions of French patients treated for digestive disorders.
While a million French people live with Alzheimer’s disease. Furthermore, a new alert scientific study on the risks associated with certain current treatments. Consequently, Published in the Revue Neurology, this research establishes the prolonged taking ofProton pump inhibitors and increased risk of dementia. Furthermore, These drugs, largely prescribed to treat gastric reflux, are used by millions of patients, often over long periods. However, This discovery raises important questions about the balance between Therapeutic benefits and long -term neurological risks.
Scientific discovery: PPI pointed out by researchers – Here 3 drugs can increase
Neurology study reveals unexpected neurological risks – Here 3 drugs can increase
The specialized review Neurology here 3 drugs can increase published a major study establishing a link between the prolonged taking of inhibitors of the proton pump. Consequently, the increase in the risk of dementia. For example, This research shows that a use of these anti-reflux treatments for four. In addition, a half years is a significant risk factor to develop neurodegenerative pathologies, including Alzheimer’s disease. Furthermore, This discovery upsets the perception of these drugs considered mild by many patients. practitioners, revealing Neurological side effects Until then undervalued in the benefit-risk balance of these current prescriptions.
Massive. often inappropriate use of PPIs – Here 3 drugs can increase
A survey by the 2015 drug security agency and a 2019 health insurance study reveal a problematic use of these treatments in France. PPIs are prescribed too frequently and for sometimes excessive durations, exceeding official recommendations. This drug surprise concerns millions of patients treated for gastric reflux, often without regular reassessment of the here 3 drugs can increase need for treatment. The High Authority for Health emphasizes. however, that these drugs should be used in until minimal effective and for the shortest possible duration.
Action mechanisms. associated risks identified
Le Profeseur Kamakshi Lakshminarayan Alerte: “Proton pump inhibitors are a useful tool for helping to control acid reflux, but long -term use has been associated in studies prior to a higher risk of stroke, bone fractures and chronic kidney disease“. Ces Multisystem risks Added to neurological concerns, creating a more complex security profile. Researchers question the biological mechanisms explaining this association, evoking disturbances in the absorption of certain essential nutrients to brain operation.
Alzheimer’s: clinical implications. recommendations for patients
Revaluation required of long -term prescriptions
This discovery requires a systematic reassessment of long -term PPI prescriptions. Doctors must now integrate the risk of dementia in their benefit-risk analysis. especially in elderly patients here 3 drugs can increase or with neurological risk factors. “”Some people take these drugs regularly. so we examined if they were linked to a higher risk of dementia“, explique kamakshi lakshminarayan. Cette Reinforced medical vigilance must be accompanied by increased neurological monitoring in patients under prolonged treatment, with regular cognitive assessments.
Therapeutic alternatives. withdrawal strategies
Faced with these new risks, the exploration of therapeutic alternatives becomes a priority for long -term PPI patients. Dietary changes, weight loss, smoking cessation and raising of bed head can significantly reduce reflux symptoms. H2 antagonists, although less powerful, constitute a drug alternative interesting for some patients. The gradual withdrawal of PPI must be supervised medically to avoid the rebound effect of acid hypersecretion. particularly problematic after prolonged treatment. Also, a study revealed that taking this sleeping pill would slow down the disease.
Neurological monitoring. early detection
Long -term PPI patients require specific neurological monitoring, here 3 drugs can increase with regular cognitive assessments to detect any signs of decline early. This preventive monitoring allows you to quickly identify the first symptoms of cognitive disorders And to adapt the therapeutic strategy. According to AuFeminin. healthcare professionals must inform their patients of the new risks identified, allowing an enlightened shared decision on the pursuit or stopping treatment. This preventive approach is part of a personalized medicine taking into account the individual risk profile of each patient.
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