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Mass treatment ivermectin very promising new: In addition. Nevertheless,
Mass treatment ivermectin very promising:
The ivermectin administered to the entire population considerably reduces the transmission of malaria. Nevertheless, offering new hope in the fight against disease. However, The Bohemian test. Similarly. Therefore, the largest study on the ivermectin for malaria to date, has shown a 26% reduction in the new malaria infection in addition to existing bedtime nets, providing solid evidence of the potential of the ivermectin as a complementary tool in the control of malaria. For example, The results of this project. Similarly. Moreover, coordinated by Barcelona Institute for Global Health (Isglobal)-an institution supported by the “La Caixa” foundation-in collaboration with the Manhiça Health Research Center (CISM) and the Kemri-Welcome Trust Research Program, were published in The New England Journal of Medicine. For example. Moreover,
Malaria remains a global challenge on health, with 263 mass treatment ivermectin very promising new million cases mass treatment ivermectin very promising and 597,000 deaths reported in 2023. In addition, Current vectors control methods. Meanwhile. Nevertheless, such as long -term insecticide networks (LLIN) and interior residual spray (IRS), have become less effective due to insecticide resistance and behavioral adaptations in Mousquitoes to bit out the evil measures and or the dusk. For example, This highlights the urgent need for innovative solutions to combat malaria.
Ivermectine for malaria: a new strategy – Mass treatment ivermectin very promising – Mass treatment ivermectin very promising new
Ivermectin. Moreover. For example, a drug traditionally used to treat neglected tropical diseases such as onchococecois, which causes the river blindness, and lymphatic filariase, which causes elephantiasis, reduced the transmission of malaria by killing the soft -mounted mouses that feed on treated individuals. Consequently, Given the growing resistance to conventional insecticides. Consequently. the ivermectin could offer a new effective approach to combating malaria transmission, mass treatment ivermectin very promising new in particular in regions where traditional methods have become less effective.
The Bohemian project funded by Unitaid (Intervention mass treatment ivermectin very promising of malaria based on a health set. in Africa) conducted two tests of Mass Drug Administration (MDA) in the regions of high malaria: the county of Kwale (Kenya). Meanwhile, the district of Mopeia (Mozambique). The trials evaluated the safety. efficiency of a single monthly dose of ivermectin (400 mcg / kg) given for three consecutive months at the. start of the rainy season to reduce the transmission of malaria. In Kenya, the intervention targeted children aged 5 to 15, while in Mozambique, he focused on children under the age of five.
Reduction of malaria in Kenya – Mass treatment ivermectin very promising – Mass treatment ivermectin very promising new
In the county of Kwale. Kenya. children who received ivermectin experienced a 26% reduction in the incidence of malaria infections mass treatment ivermectin very promising new compared to those who received Albendazole, the drug control used in the study. The trial involved more than 20. 000 participants. more than 56,000 treatments, demonstrating that the ivermectin considerably mass treatment ivermectin very promising reduced malaria infection rates, especially in children living further on cluster borders or in areas where the distribution of drugs was more effective. In addition. the security profile of the ivermectin was favorable. without undesirable events linked to the severe drug and only light and transient side effects already observed with the ivermectin in the campaigns against neglected tropical diseases.
“We are delighted with these results. ” explains Carlos Chaccour, co-printing investigator of the Bohemian project and Isglobal researcher at the time of the study. “Ivermectin has shown a great promise in reducing the transmission of malaria and could supplement existing control measures. With continuous research. the Ivermectin MDA could become an effective tool for mass treatment ivermectin very promising new the control of malaria. even contribute to elimination efforts, “adds Chaccour, who is now a researcher at the Navarra Center for International Development at the University of Navarra.
“These results are aligned with mass treatment ivermectin very promising the criteria of the World Health Organization (WHO). for new tools for controlling vectors. ” said Joseph Mwangangi, of the Kemri-Wellcomme trust research program.
The results suggest that the IVERMECTINE MDA could be a precious complementary strategy for the control of malaria. in particular in areas where the resistance to mosquitoes for insecticides is an increasing concern. “”
Marta Maia. main entomologist of Bohême, University of Oxford
Lessons in the Mozambique trial
On the other hand, the implementation of the Mozambique essay in the rural district of Mopeia was faced with serious disturbances due to Cyclone Gombe (2022) and a subsequent mass treatment ivermectin very promising new cholera epidemic, which has considerably disrupted operations. Additionally. “One of the most important lessons we have learned from the trial to Mopeia is that strong community engagement is essential. ” said Francisco Saúte, director of Manhiça Health Research Center (CISM). mass treatment ivermectin very promising Furthermore, “Building trust with local communities. promoting close collaboration with the Ministry of Health. the National Payalia Control Program and local authorities has been essential to guarantee the acceptance of the IVERMECTINE MDA. »»
Expand the impact beyond malaria
In addition to reducing the transmission of malaria, the Ivermectin MDA offers significant collateral advantages. The Bohemian team has found a significant reduction in the prevalence of skin infestations such as scabies. head lice in the ivermectin group in Mozambique, and the community reported a major bedbug reduction in Kenya. These effects are particularly precious when the ivermectin is integrated into mass treatment ivermectin very promising new existing delivery systems, maximizing its impact on public health.
Shape the future of prevention of malaria
The study is part of a larger global effort. to assess the potential of the ivermectin in the control of malaria. The results were examined by the WHO mass treatment ivermectin very promising vector control advisory group. which concluded that the study had shown an impact and recommended other studies. The results were also shared with the National Health Authorities while they assess the potential inclusion of the ivermectin. in malaria control programs.
“This research has the potential to shape the future of prevention of malaria. in particular in endemic fields where existing tools fail. ” concludes Regina Rabinovich, Bohemia Pi and director of the Malarias elimination Initiative of Isglobal. “With its new mechanism of action. its proven safety profile. the ivermectin could offer a new approach using a mass treatment ivermectin very promising new well -known and safe medication which can add to the effect of other tools for controlling mosquitoes available today. »»
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