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Only one injection to make the breast cancer tumor disappear? The hopes of a new therapy

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Only one injection make breast new: In addition. Similarly,

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Breast cancer remains one of the most common cancers in the world. Meanwhile. Nevertheless, Although medical progress has enabled many patients to survive, current treatments are often heavy and can have significant side effects. Meanwhile, Although effective, these treatments are often long, trying and associated with various health risks of patients. However, a discovery could revolutionize this approach and offer hope for faster and less painful treatment.

Traditional treatment. Furthermore. its limits – Only one injection make breast – Only one injection make breast new

The breast cancer with positive estrogen receptors (ER+) is a cancer subtype in which tumor cells have receptors that bind to estrogen, a hormone that stimulates their growth. Meanwhile, This type of cancer represents around 70 to 80 % of cases of breast cancer. Furthermore, Standard treatment for ER+ breast cancer is generally based on a combined approach: surgery only one injection make breast new to remove the tumor. In addition, followed by hormonal treatments which often last several only one injection make breast years. These treatments aim to block the action of estrogen, which thus limits the growth of remaining tumor cells.

Although these treatments considerably increase the chances of healing and survival, they are frequently accompanied by many undesirable side effects. Patients can suffer from muscle and joint pain, hormonal disorders, sexual disorders and significant fatigue. In addition. hormonal treatment is linked to long -term risks. in particular the weakening of bones and an increased risk of developing other types of cancer, such as that of the endometrium.

Another major problem remains Risk of recurrence cancer, even after several years of treatment. About 20 to 30 % of patients treated for ER+ breast cancer will indeed have a recurrence. often several years after the end of treatment. These factors highlight the urgent need for more only one injection make breast new effective, less invasive and better targeted treatments.

For these reasons. research turns to new therapies capable of specifically treat cancer only one injection make breast cells while reducing side effects. the risk of recurrence. Such advances could transform the way in which this cancer is treated in the future, offering new perspectives to patients.

Research on a new drug

Dr. Paul Hergenrother and his team at the University of Illinois in Urbana-Champaign, in the United States. have developed a drug based on small molecules. baptized ERSOdesigned to eliminate tumor cells in a targeted and less invasive way. This medication acts by inducing the necrosis of cancer cells. a process in which cells swell and eventually die, which reduces the tumor. The first tests carried out on mice showed promising resultswhich confirms the effectiveness of the drug in the destruction. of tumor cells. However, Erso had certain undesirable side effects, which limited its potential only one injection make breast new for clinical use.

In order to overcome these limitations, Dr. Hergenrother and his team modified the molecule to create a derivative called ErSO-TFPy. However. only one injection make breast this new version seems not only more effective, but also safer with considerably reduced side effects. Additional tests carried out on several murine models of ER+ breast cancer have shown that erso-TFPY makes it possible. to eliminate almost completely the tumors with a single dose while limiting animal health risks. This advance opens the way to potentially revolutionary, more targeted and less invasive treatment for patients with ER+breast cancer.

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Crédits :MOHAMMED HANEYYA NEZAMUDEEN/ISTOCK

A promising future. but with limits

Despite these promising results, published in the journal ACS Central Science, it is important to emphasize that these only one injection make breast new discoveries only one injection make breast are still at a preclinical stage. Although theErSO-TFPy has shown great efficiency in Murine models. there are important obstacles to overcome before this medication can be used in humans. The human body is indeed much more complex than that of laboratory animals and biological reactions can be very different.

Researchers thus recognize that it is necessary to continue clinical tests. carry out more in -depth studies to verify whether this treatment could be as effective and safe for humans. However. the results obtained in animal models are encouraging enough to arouse real hope as to the possibility of one day having a much simpler. less invasive breast cancer treatment.

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Further reading: ADHD: rise of psychostimulants in France, between catch -up and prudence: newsDespite new drugs, global management remains necessaryMy ophthalmos cannot come back from the effects on my visionIts growth pains were actually rare bone cancer“With sedentary lifestyle and its misdeeds, we are witnessing the emergence of a new social condition”.

nova.caldwell
nova.caldwell
Nova covers Pacific-Northwest volcano science, turning seismograph squiggles into edge-of-seat cliffhangers.
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