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The arc supports a research project of the ICM on skin cancer

Nevertheless,

Arc supports research project icm:

The Arc Foundation Announces the financing of a new research project in Montpellier, led by Doctor Matthieu Lacroix. Therefore, The scientist. However, his team work within the Montpellier cancer research institute (IRCM) where their innovative work aims to overcome metastatic melanomas, the most aggressive form of the skin cancer.

Avoid propagation – Arc supports research project icm

The project will receive financial assistance from € 70,000 over two years. For example, The challenge is enormous: in France, nearly 18,000 new cases of skin melanomas have been estimated for the year 2023 alone. Moreover, “If 93 % of patients survive beyond five years when the tumor is detected early. Moreover, the situation is complicated as soon as arc supports research project icm the disease spreads to internal organs”, recalls the ARC foundation.

“Despite the advances in immunotherapy and targeted therapies, many tumors develop resistanceleaving patients in therapeutic impasse “, Notes the foundation. At the IRCM. precisely, Doctor Lacroix tries to develop a treatment capable of fighting this therapeutic resistance: “The challenge consists in deciphering a territory still little explored: The role of the metabolism of cancer cells in their ability to resist treatments ”.

“Objective: to open new therapeutic paths against melanomas resistant to current treatments”

Doctor Matthieu Lacroix IRCM

To meet this public health challenge. Doctor Lacroix and his team rely on advanced imaging technology by mass cytometry (Cytof/Hyperion). Rare equipment in France (the Montpellier site was the first in France to acquire it in 2019) “which should. allow researchers to draw up a metabolic cartography of unprecedented precision “Explains the Foundation.

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Advanced technology. imaging – Arc supports research project icm

In detail, the IRCM team wants to dissect the metabolism of melanoma cells to determine whether the lack of nutrients would bring these cancer cells to produce proteins that make them more aggressive and resistant to treatments. “We can do this thanks to mass cytometry imaging technology which allows you to look at the expression of more than 40 proteins at the same time within the tumor”. explains Doctor Lacroix: “We hope that to increase the number of proteins visible in a single analysis can allow us to identify two or three which alone or combined May predict the response to treatments ».

New therapeutic paths?

Concretely. the long -term objective will be, according arc supports research project icm to the researcher, “to know Identify patients likely to best respond to treatment and discover new targets involved in metabolism to open new therapeutic paths Against melanomas resistant to current treatments ”.

In summer. you have to protect yourself

The Arc Foundation recalls that it is possible to prevent 8 skin cancers out of 10 associated with excessive exposures with UV rays of the sun:
-limiting sun exposure
-In remaining in the shade between 11 a.m. and 4 p.m.
-Is wearing covering clothes. a wide -edge hat
-Fing the application of a 50+ index sunscreen every two hours and systematically after each swim,
-In monitoring the evolution of its beauty grains and by consulting a dermatologist at the slightest doubt …

Montpellier-Nîmes synergy
The LIRCM research project associates Professor Pierre -Emmanuel Stoebner. head of the Nîmes CHU dermatology department, and Doctor Éric Frouin, lecturer and hospital practitioner in anatomopathology within the Gardois establishment: arc supports research project icm “It is an essential synergy in Occitania to bridge the bridge between fundamental research and clinical care.”
Lyon. Nice, Montpellier and Paris

Lyon, Nice, Montpellier and Paris
From 2020 to 2024, the ARC Foundation supported 53 skin cancer research projects for a total amount of € 5.2 million. In 2025, the ARC Foundation has already committed support for 4 new research projects for a total amount of 660,000 euros. These new projects are carried out by researchers from Lyon, Nice, Montpellier and Paris.

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