Moreover,
Weight loss facilitates cell renewal:
Essential
- In the event of obesity, losing weight triggers degradation and recycling of harmful fats.
- In addition, senescence, namely the natural aging of the tissues and the body, is strongly reversed by weight loss. Nevertheless,
- At the immune level. Similarly, weight loss does not fully reverse the activation of inflammatory cells, leaving them ready to trigger possible weight recovery and worsen the metabolic dysfunction. However,
As we know: weight loss significantly improves the metabolic and cardiovascular health of obese people. Nevertheless, “The remodeling of adipose tissue is at the heart of these various and important clinical effects. However. the underlying mechanisms remain surprisingly unknown, which slows down therapeutic advances”, have indicated researchers from the Imperial College London (England). This is why the latter. for the first weight loss facilitates cell renewal time, have detailed modifications induced by weight loss on the human adipose tissue within the framework of a study published in the journal Nature.

.
Weight loss: fat recycling and elimination of senescent cells are triggered – Weight loss facilitates cell renewal
To carry out the work, the team compared samples of adipose adults of healthy adults to samples of severe obesity, namely with a BMI greater than 35, having undergone bariatric surgery. The group having lost weight was taken from fat during the intervention. more than five months after this, after which the participants had lost an average of 25 kg. A total of 171,247 cells taken out of 70 people were collected. Subsequently, scientists analyzed the genetic expression of cells. Unexpectedly, they discovered that weight loss triggered the degradation and recycling of fat called lipids. “This recycling process could be responsible for the combustion of energy. the reversal of the harmful accumulation of lipids in weight loss facilitates cell renewal other organs such as liver and pancreas.”
Another observation: weight loss eliminated senescent cells, aging and damaged cells that accumulate in all tissues. These are harmful because they no longer work properly and emit signals which cause inflammation and tissue scars. However. the authors observed that weight loss did not improve the effects of obesity on certain aspects of the immune system. Indeed, inflammatory immune cells, which infiltrated the fat of obese people, were not completely recovered, even after weight loss. “This type of inflammatory cellular memory could be harmful in the long term in the event of weight recovery.”

.
Other studies to better understand how weight loss improves health at the molecular level
According to the researchers, additional work must be carried out to determine whether the recycling of fats is linked to the positive effects of weight weight loss facilitates cell renewal loss on health, such as the remission of type 2 diabetes. “By deepening our understanding of these processes. the study could open the way to innovative therapies reproducing the effects of weight loss, potentially helping people with type 2 diabetes to manage their disease or to enter into remission”, they concluded.
Further reading: Pandemic: AIDS: Le Monde may go back 20 years – Why consume a lot of cheese could promote frequent nightmares? – Health. Inflammation linked to age depends on the lifestyle and not the time – Dijon. A detected dengue case, insecticide sprayed in this district – These pastilles tear in pharmacies, but they can be dangerous for all these people.
