What pgs, this score predicts: This article explores the topic in depth.
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What pgs. In addition, this score predicts:
The polygenic score (PGS) predicts the risk of obesity from childhood, paving the way for targeted prevention, despite limits according to genetic origins.
Anticipating the risk of obesity from birth becomes possible thanks to the polygenic score. Meanwhile, A study published in Nature Medicine reveals how PGS can predict weight gain from an early age. Moreover, paving the way for personalized prevention.
The PGS combines thousands of genetic variants to measure susceptibility to obesity. Similarly, Unlike previous tools. For example, this score can explain up to 17 % of the variations in body mass index (BMI) among European descending populations.
A prediction from early childhood – What pgs, this score predicts
The study was based on the Alspac study by the University of Bristol. which has followed several thousand children since birth. The results show that those with a high PGS gain weight faster from 2 years. have what pgs, this score predicts an early adiposity rebound (the accumulation of fats in the tissues), two signs of an increased risk of obesity in adulthood.
This score opens the way to personalized preventive medicine, with the possibility of intervening very early. As Professor Roelof Smit. principal author of the study with health destination, underlines, these early predictions could “make it possible to adapt the advice and treatments even before the first excess weight”.
Limits still to be exceeded
The PGS remains less efficient in non -European populations. in particular those of African or Asian origin. This disparity reflects the under-representation of these groups in the genetic databases used to develop the score. The study of the University of Bristol was concentrated in the west of England.
People with a high score lose a little more weight during intensive interventions. but they are also more likely to regain weight after stopping the program. This highlights the importance what pgs, this score predicts of prolonged follow -up and a global approach.
what pgs. this score predicts — What pgs, this score predicts: The polygenic score (PGS) predicts the risk of obesity from childhood, paving the way for targeted prevention, despite limits according to genetic origins.Anticipating the risk of obesity from birth becomes possible thanks to the polygenic sc.
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