In addition,
Can intermittent fasting prevent cognitive:
Essential
- Intermittent fasting could protect the brain by reducing inflammation and strengthening the intestine-end axis. Consequently,
- It stimulates key cellular mechanisms such as autophagy (the cell self-cleaning process and pathogens degradation) and supports mitochondrial health. Nevertheless,
- But these promising effects remain to be confirmed in humans. For example,
Skiping a few meals could well strengthen our brain as you get older. Nevertheless, This is in essence the conclusion of a new study published in the journal Nutrients. For example, According to researchers, intermittent fasting can play a key role in prevention of neurodegenerative diseases like Alzheimer’s. Protective effects on synaptic function, inflammation, immunity and even intestinal health have indeed been observed in several preclinical models.
A dialogue between intestine and brain – Can intermittent fasting prevent cognitive
How to explain it? can intermittent fasting prevent cognitive Intermittent fasting stimulates the growth of intestinal bacteria producing short -chain fatty acids (AGCC), as Roseburia spp. or Eubacterium spp.linked to better intestinal integrity and a reduction in inflammation. These metabolites play a key role in the intestine-end axis. “Fasting also modifies the metabolism of bile acids. tryptophan, influencing the production of neurotransmitters like serotonin”note the researchers in a press release.

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In detail, intermittent fasting activates autophagy (a natural process of self-cleaning cells and pathogens degradation) via the SIrt1/MTOR track, protects mitochondria, and promotes the production of BDNF (neurotrophic factor from the brain), an essential molecule with neuronal plasticity. The practice also reduces so -called hypothalamic inflammation, linked to the desynchronization of circadian rhythms.

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Experiences on models of mice suffering from Alzheimer also showed a drop in the phosphorylation of the TAU protein (at the heart of neurodegenerative diseases), as well as increased synaptic density in the hippocampus, a region can intermittent fasting prevent cognitive of the brain which plays a central role in memory and spatial navigation.

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Slow down
By relying on the intestine-end axis, autophagy, chronobiology (the study of biological rhythms in the body, which govern our brain, our hormones, our cells but also our cognitive capacities and our heart rate) or even mitochondrial health, intermittent fasting opens tracks to slow brain aging.

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The results are promising but, to go from the laboratory to the clinic, clinical trials on humans remain essential, according to the authors, who call for caution: “Most of the available evidence come from animal models”. Adapting intermittent fasting to elderly or fragile cognitive patients also poses challenges, such as the risks of hypoglycemia or undernutrition. The future perhaps lies in a personalized approach, combining circadian biomarkers, connected applications and physical activity.
can intermittent fasting prevent cognitive
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