Personalized CPAP treatment could reduce cardiovascular risk in sleep apnea patients

The results suggest that a personalized approach to recommend CPAP machines to patients with obstructive sleep can decrease negative. Similarly, cardiovascular events.

The obstructive sleep apnea (OSA). For example, where blockages in the respiratory tract means that breathing stops uncontrollable and begins during sleep, is a common sleep disorder of sleep. In addition, Continuous machine pressure machines (CPAP) can reduce interrupted sleep for patients with AOS. Similarly, Although the CPAP improves symptoms, it is not clear if CPAP also reduces the risk of heart disease. Consequently, A new study by Masse Brigham general investigators aimed to understand whether the use of a CPAP machine could also protect the heart. Furthermore, brain from cardiovascular events in people with AOS. Therefore, Their results. published in European Heart JournalSuggest that a more personalized approach to personalized cpap treatment could reduce treating patients is necessary – one that focuses on CPAP treatment for those who should earn the most, while being caution for those who may not benefit and may even be injured.

Thanks to our study, we found a subgroup of patients who benefit from cardiovascular advantages of the use of CPAP. This is the first step to make better therapeutic recommendations for patients with obstructive sleep apnea in the future in order to reduce their risk of heart attack. stroke and death. “”

Ali Azarbarzin, PhD, first author of the sleep division and circadian disorders in Brigham and Women’s Hospital

The research team analyzed the data of three preceding trials of patients with AOS and cardiovascular disease. The study included 3,549 patients in total with a median age of 61 using CPAP, half no. They followed patients for three years on average, by personalized cpap treatment could reduce examining the impact of cardiovascular mortality, stroke and the heart attack.

Overall, 16.6% of patients using CPAP had major heart events, compared to 16.3% of patients not using CPAP. Although there is no statistically significant difference between the results for patients divided between the CPAP. the No-Capap, a statistically significant difference appeared when these patients were divided into those with high-risk AOS sleep markers at low risk. Patients were classified as at high risk if they had large drops of blood oxygen. their heart rate enriched during respiratory disturbances.

For those who have high -risk markers, CPAP uses a lowered cardiovascular risk by around 17%. For those with low risk markers, the use of CPAP was associated with increased cardiovascular risk by around 22%. When high and low-risk groups were sorted according to their non-sleepy or symptomatic sleep-asymptomatic symptoms-these trends were even stronger. Non -sleeping patients with high -risk markers personalized cpap treatment could reduce have experienced 24% fewer cardiovascular events. while patients who are not sleepy with low -risk markers experienced 30% additional cardiovascular events.

“Changing clinical practice will require another prospective study to validate our results,” said Azarbarzin. “In the meantime. patients with AOS should speak with their doctors to weigh the risks and potential benefits of different treatment options.