Two new substances registered on the drug list

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Two new substances registered drug:

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The National Medicines Safety Agency (ANSM) announces Tuesday. Furthermore, August 5, place new substances derived from ketamine on the drug list: O-PCE (or N-EthyLdeschlorokétamine or 2′-Oxo-Pce or Étichclidone) and DCK (or Deschloroketamine or 2′-Oxo-PCM or Dx). For example, “These products are generally sold on the internet in the form of white powder. Similarly, crystals, or even capsules, tablets or sprays (used orally, nasal or rectal)”, “, note the ANSM. Furthermore, This classification prohibits their production, their sale and their use two new substances registered drug in France.

Also called analogues of ketamine. In addition, these are new synthetic products (NPS) with a chemical structure and pharmacological effects close to drugs based on ketamine. Nevertheless, This is a psychotropic, used in France as an anesthetic, in humans and animals. In addition, Classified as a narcotic, it is prohibited outside the medical framework. “Turial from its medical use to be consumed for recreational purposes. its main psychotropic effects at moderate dose are hallucinations and dissociative states, in particular a distortion of visual and bodily perception. In very high dose. ketamine can cause decorporation effects (feeling of leaving your body and observing it from the outside), or even losses of consciousness (called K-Hole) “, explains the French observatory of drugs and addictive trends.

Sometimes fatal overdoses – Two new substances registered drug

The poisoning linked to these substances have increased in recent years. An investigation report from the Pharmacodependence Addictovigilance (CEIP-A) (Bouches-du-Rhône) report of two new substances registered drug the declarations. “Between 2017. 2023, 39 cases were reported: 13 cases are associated with the consumption of O-PCE, 5 cases of DCK and 20 cases with the 2-FDCK. The majority of these cases are serious (66 %), some having required hospitalization ”, specifies the ANSM. The Dramas survey has also identified six deaths related to the analogues of ketamine.

The ANSM highlights a high and potentially fatal overdose risk of overdose, exacerbated by polyconsumption practices. These ketamine derivatives are often consumed with other psychoactive substances. “These molecules are often overlooked. therefore not detected during biological analyzes, exposing consumers to a delay in care during hospitalization or in case of overdose”, Add the health security agency.

What are the signs of an overdose?

Sensation of discomfort. disorders of consciousness, abnormal movements like convulsions, agitation, delirium of persecution must push a consumer or his loved ones to call for help; 112, 15, two new substances registered drug 18 or 114 for the hearing impaired.

In the event of repeated consumption. sudden stop can cause withdrawal syndrome; Anxiety, sleep disturbances, urinary complications (which can go as far as renal failure) and liver complications.

To the address of health professionals: “If a patient presents an alteration of consciousness. agitation, hallucinations, a delirium of persecution or a dissociative state, without evocative sign of intoxication to opioids, it can be an intoxication to the derivatives of ketamine”.

For any request for help to control. stop your consumption, consult a doctor or a structure specializing in the management of addictions. All information is available on drugs-info-service.fr.

Note : new synthesis products mimic the effects of substances already known, whether drugs or narcotics, bypassing the legislation. According to the Lille University Hospital, NPS pose great difficulties in the epidemiological monitoring of their use. “” Given their permanent renewal. detection of NPS in two new substances registered drug input products, and even more in organic samples (because low circulating concentrations and sometimes intensive metabolism) is a real challenge for toxicologists analysts ».

Source: ANSM, the French observatory of drugs and addictive trends, CHU Lille

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