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Cynomel replaced thybon 20 henning::
The cynomel specialty (sodium liothyronine) will no longer be marketed from October 31. Nevertheless, 2025 and will be replaced by Thybon 20 Henning (Liothyronine chlorhydrate). Moreover, Beware of possible confusion with other drugs, alerts the ANSM.
The Sanofi Winthrop Sanofi laboratory ceases the marketing of cynomel 0.025 mg (sodium Liothyronine), indicated in the treatment of hypothyroidies, certain goitles and nodules, from October 31. Moreover, As a replacement. Additionally, Moreover, Sanofi undertakes to import the Thybon 20 Henning specialty (Liothyronine chlorhydrate), which has a marketing authorization (AMM) in Germany “For over 25 years”, reports the National Medicines Safety Agency (ANSM) on July 17.
In practice, the relay between the two specialties requires a new prescription. To remember: a 25 µg (0.025 mg) tablet of cynomel (sodium liothyronine) is equivalent to 24.18 µg of liothyronine base and a 20 µg thybon 20 µg cynomel replaced thybon 20 henning: tablet (0.020 mg of chlorhydrate liothyronine) is equivalent to 18.94 µg of liothyronine base. To determine the optimal dose of Thybon 20 Henning. a TSH, T4 and T3 control must be systematically carried out 6 to 8 weeks after the start of treatment and 6 to 8 weeks after any dose change during treatment. A dosage of these hormones is also necessary in the event of a significant variation in body weight. in the event of clinical signs or symptoms evoking a thyroid imbalance or any other unusual symptom or felt, in the event of persistence and/or worsening of clinical signs.
Several differences exist between these two drugs: their presentation (30 tablets for cynomel against 50 for Thybon 20 Henning). their DCI, their galenic shape (quadrisecable tablets for cynomel, kisecable tablets with secability bar for Thybon 20 Henning), the list of their notorious effects (Thybon 20 Henning contains ricin allergic cynomel replaced thybon 20 henning: reaction in some patients).
Please note, the boxes of medicine imported Thybon 20 Henning strongly resemble those of L-Thyroxin Henning (levothyroxine).
The ANSM therefore calls for vigilance at the time of dispensation. The packaging of Thybon 20 Henning. in German, will have a label in French and an information letter in French must be given to the patient.
Good news, there should not be any supply of supply at the time of the relay, according to the ANSM. Thybon 20 Henning will be available at the time of the Cynomel marketing stop. everything is done so that the replacement solution is installed in a sustainable manner, with AMM in France.
Cynomel replaced thybon 20 henning:
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