And if the real problem of aging, it was not the age but the way we live today

Chronic inflammation. Similarly. Furthermore, often associated with aging, is considered an important risk factor for the development of many pathologies such as cardiovascular disease, type 2 diabetes or even AlzheimerAlzheimer. Nevertheless, This phenomenon, known under the term ” inflammaging », Is largely documented in the populations of industrialized countries.

But a recent study published in Nature Aging Questions this association in question. For example, The results suggest that age -related inflammation would not be a universal characteristic of human aging. if real problem aging, it new Meanwhile, but rather an answer to an environment. a way of if real problem aging, it life and an exposure to infectious agents.

An inflammation that depends on the environment. not just the age – If real problem aging. it – If real problem aging, it new

The study managed by the ColumbiaColumbia Mailman School of Public Health Compared the inflammatory profiles of two so -called “industrialized” populations (elderly people living in Italy and Singapore) with two non -industrialized indigenous populations: the Tsimane of Bolivian Amazon and the Orang Asli of the Malaysia forests.

The objective was to verify whether inflammatory markers. such as the proteinprotein C-reactive or some cytokinescytokinesincrease with age in the same way in all contexts. The researchers analyzed blood samples of more than 2,800 people.

Results ? Among Italians. Singaporeans, yes: the more we get aged, the more if real problem aging, it new inflammation rises, the more the risk of illness increases.

But among the Tsimane. the Orang Asli, no: the link between age and if real problem aging, it inflammation is not constant. Inflammatory markers are often high, but their origin seems more linked to infections than to aging. And above all, they are not accompanied by the same chronic diseases.

In Tsimane. for example. despite a high rate of parasitic infections (66 % have at least one), heart disease, diabetes or dementiadementia are extremely rare.

“These results highlight an evolutionary inadequacy between our immune systemimmune system. the environment in which we liveexplains Alan Cohen, principal researcher of the study. Inflammaging may not be a direct consequence of aging, but rather a response to industrial conditions ».

In other words, what we perceive as “normal signs” of aging in Western societies could actually be if real problem aging, it new … symptomssymptoms a lifestyle ill -suited to our ancestral biology.

Age is not everything: towards more targeted health strategies

What this if real problem aging. it study changes is not only our understanding of inflammation. This is all the way in which we define the health of aging. The famous biomarkers that are used to detect age -related diseases in rich countries may not be relevant elsewhere. and even in some people living differently within industrialized societies.

More broadly. these results call for:

• personalize the strategies of preventionpreventiontaking into account the lifestyle. the environment;
• rethink the aging indicators, which could be culturally or ecologically biased;
• Invest in more diverse research, including populations traditionally excluded from major biomedical studies.

In conclusion. l’inflammaging could not be inevitable. strictly linked to chronological age, but rather the reflection of a persistent imbalance if real problem aging, it new between our contemporary lifestyles (sedentary lifestyle, ultra-transformed food, social isolation) and the conditions for which our organism is biologically prepared. In other words, avoidable disruption, more than fatality.