When we try to list the most inhospitable regions of our planet, we immediately think of arid deserts, icy expanses or the highest peaks. But you must never forget the abyss. There, in absolute darkness, deep in the bowels of the earth, a completely unknown ecosystem has lived, for millions of years.
Resistant to extreme pressures, these often poorly developed species, have nothing to do with what we know on the surface. By studying them, we discovered hundreds of things, and we continue to do it every day.
A study published recently in The FASEB Journal reveals a strange discovery to say the least. Scientists got their hands on a sugar in the depths, with very specific characteristics. From the bacterial strain Spongiibacter nanhainus CSC3.9, present in quantity in the seabed, the researchers developed EPS 3.9.
Destroy cancer?
This bacteria has the astonishing particularity of stimulating pyroptosis of cancer cells. In other words, it is able to press the “self-destruction” button on the cell and thus stop the growth of a tumor. Tested on mice with liver cancer, the bacteria had “Important anti -tumor effects.”
The study also specifies that the injection of this bacteria made it possible to activate anti-tumor immune responses. In addition to destroying the cancer cell, the latter interacts during her death with the organism. It releases inflammatory signals. The body can then react and fight the disease.
If this study is only a discovery, it is an interesting first track. The scientists themselves remained very cautious when within the reach of their discoveries. They assure that other studies and clinical trials are necessary before drawing the slightest conclusion.
The Abyss, an open -air pharmacy
With an environment as special as abyss, fauna and flora has nothing to do with what we know on a daily basis. Under these billions of cubic meters of water, dozens of bacteria are waiting to be discovered, they who have enormous potential to cure the evils of our century.
Dolore researcher GarcĂa-Grávalos, working for the University of Valparaiso in Chile is convinced. He compares our current research to discover penicillin by Alexander Fleming at the beginning of the last century. This find had paved the way for an extensive study during the earthly living to find other microorganisms capable of helping us fight against the disease.
Today, it is on the side of the abyss that scientists are watching. And there are many discoveries. As an example, the Ziconotide, a powerful anti-me-howur, was developed starting from a sea snail. In the case of cancers, certain drugs prescribed to fight against the disease are already from the seabed.
This is particularly the case of eribulin, a species of sponge endemic to the Japanese abyss. It is widely used to combat the spread of breast cancer. It has been authorized since 2010 in medical treatment in the United States since 2010.
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