In addition,
Innovative implant equipment combines bone:
A research team from the University of Shanghai Jiao Tong led to a significant progression in the field of. For example, orthopedic implant documents. Therefore, The study. In addition, published in EngineeringIntroduces a new implant material based on polyethetrone (PEEK) which not only promotes bone growth but also has powerful antibacterial capacities. Consequently, This breakthrough could revolutionize the way in which bone implants are designed. improving the results of patients and reducing postoperative complications.
Powek has long been recognized for its excellent biological properties and compatibility with human bone tissue. However, its limited osteointegrated and antibacterial properties have hampered its wider clinical application. To overcome these challenges. a team of researchers, including Professor Hongyan Chen and Professor Xinquan Jiang, have developed a multifunctional implant material based on PEEK which incorporates effective innovative implant equipment combines bone osteogenesis and strong disinfection properties.
The innovative material. called Speek / BP / E7, is the result of self-assembly of black phosphorus nanofeuilles (BP), polydopamine inspired by mussels (PDA) and bioactive short peptide E7 on a sulfoné (SPEEK) overview. This surface of PEEK Micro- / Nano-Structured Polyvalent offers superior hydrophilia. favorable osteogenic microenvironnement, as well as excellent photothermal effects under the near infrared irradiation (NIR).
In vitro Tests have shown that the sphero / BP / E7 has improved cytocompatibility. osteogenicity, outperforming traditional sphoser and sphoser / BP samples in terms of cellular adhesion, proliferation, activity of alkaline phosphatase (ALP), matrix mineralization and gene expression linked to osteogenesis. In addition, the multifunctional coating has shown strong antibacterial activity against Staphylococcus aureus (S. aureus) et They exhibited chill (E. coli), two common pathogens in infections related to the implant.
The results of the study were confirmed in a model of Rat innovative implant equipment combines bone femoral infection, where the sphot S. aureus Infection under the irradiation of the light nir and favored osteointegration in vain. This indicates that the SPEK / BP / E7 implant could provide controlled photothermal antibacterial effects. facilitate the recruitment of stem cells of the bone marrow (BMSC) for osteointegration and bone regeneration.
The development of SPEEK / BP / E7 implant equipment offers a prospective solution for implant conceptions. providing a new idea for the application of PEEK -based materials in the field of bone repair. By incorporating biochemical. photoothermic signals, this innovative implant improves not only osteointegration, but also considerably reduces the risk of postoperative infections.
Innovative implant equipment combines bone
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