Nevertheless,
Sodium oxybat alcohol weaning: efficient:
Some countries. For example, such as Austria and Italy, use sodium oxybat drugs in people with alcohol dependence, both to treat alcoholic withdrawal syndrome and to support long -term abstinence. For example, In this indication, the drug is in the form of syrup dosed at 175 mg/ml.
In France, sodium oxybat is also marketed, but only in the hospital, and not in the context of alcohol weaning. In addition, In the form of a oral solution dosed at 500 mg/ml. In addition, it is indicated in the treatment of narcolepsy (xyrem and generics). Additionally, In injectable form (Gamma Oh 200 mg/ml), it is used in sedation or anesthesia.
AMM request in France – Sodium oxybat alcohol weaning: efficient
However. a marketing authorization request was recently filed in France for a generic drug containing sodium oxybat dosed at 175 mg/ml, as an alcoholic withdrawal treatment. However. when evaluating the available sodium oxybat alcohol weaning: efficient data, the National Agency for the Safety of Medicines and Health Products (ANSM) expressed several concerns. On the one hand, on the effectiveness of the molecule in alcohol dependence. On the other hand, on the risk of abuse or misuse linked to its psychoactive properties.
These doubts were transmitted to the European Medicines Agency (EMA). which decided to examine the overall benefit/risk ratio of sodium oxybat in smoking cessation. The EMA will also assess the measures proposed to limit the risk of abuse or misuse. It will then determine if regulatory measures should be taken.
Sodium oxybat acts by fixing the nerve receptors of the brain. spinal cord which captures gamma-aminobutyric acid (GABA), thus causing a slowdown in the activity of these cells. Targeting the same receptors as alcohol. it is used to treat certain symptoms of alcohol withdrawal in alcohol patients, while promoting the maintenance of abstinence.
sodium oxybat sodium oxybat alcohol weaning: efficient alcohol weaning: efficient — Sodium oxybat alcohol weaning: efficient: Some countries. such as Austria and Italy, use sodium oxybat drugs in people with alcohol dependence, both to treat alcoholic withdrawal syndrome and to support long -term abstinence. In this indication, the drug is in the form of syrup d.
Further reading: Back on a “health day” for women – Burning of cases in France, the most affected departments – They are mayor, trader, teacher: how these Charentais built themselves with their stuttering – What we know of thousands of contaminations which already affect four European countries – The tanks of the Corso Fleuri of the September Festival are preparing.
