For example,
Studies alert long -term effects:
Long presented as unavoidable allies in the fight against cardiovascular disease. Therefore, statins – these hypocholesterol drugs prescribed to millions of patients around the world – are today the subject of an increasing questioning. Nevertheless, A recent summary article. For example, published in the journal Clinical Pharmacologyhighlights potentially serious side effects linked to their prolonged use: calcification of coronary arteries, nutritional deficits, and increased risk of heart failure.
A medical paradox: prevent crises by promoting atherosclerosis? – Studies alert long -term effects
The main objective of statins is to reduce LDL cholesterol levels. Moreover, often designated as “bad cholesterol”, in order to prevent atherosclerosis and its complications (infarction, stroke). However, But according to the scientific journal. Furthermore, their prolonged use could have an opposite effect: by promoting the calcification of coronary arteries, they would paradoxically contribute to accentuating the risk of heart disease.
Arterial calcification occurs when calcium studies alert long -term effects accumulates in the walls of the arteries, causing their hardening. In addition, This phenomenon hinders blood circulation and can cause infarction. However, Several studies. including one published in 2021 in the Kaohsiung Journal of Medical Sciencesestablish a link between taking statins, vitamin K2 deficit – an essential nutrient in the regulation of calcium – and progression of this calcification.
Key nutrient deficiencies: COQ10, vitamin K and selenium
Statins would act as Mitochondrial toxinsaccording to the authors of the report. By inhibiting the natural production of Coenzyme Q10 (COQ10). they would affect the functioning of muscle cells, especially those of the heart. This substance is crucial to producing ATP, the main source of cellular energy. Prolonged CoQ10 deficiency can therefore weaken heart muscle and promote heart failure.
A 2008 study. published in BioFactorshad already highlighted the improvement of the cardiac function in patients who have stopped taking statins and taken supplements studies alert long -term effects of COQ10 for almost two years.
Statins would also affect the synthesis of vitamin K – essential to avoid vascular calcification -. proteins carrying selenium, another mineral involved in heart health.
Often ignored. underestimated side effects
According to the authors, doctors prescribing statins are not always aware of these undesirable effects. Heart insufficiency. diagnosed in certain treated patients, is often attributed to other factors such as age or hypertension, rather than the treatment itself. This ignorance would pose an ethical problem: “the principle of informed consent requires preventing patients from the risks. including those related to heart failure”, recall researchers.
With more than a million annual hospitalizations for heart failure just in the United States. these conclusions deserve attention, especially since they are added to other alarming publications. A 2022 study. published in Arteriosclerosis, Thrombosis, and Vascular Biologyalso established a link between statins and chronic inflammation, another track explaining their studies alert long -term effects impact on arterial calcification.
Far from calling for the generalized judgment of statins. this research underlines the need for a more nuanced and individualized approach. COQ10 supplementation. special attention to vitamin K2 status and better patient information could help reduce the risks associated with these long -term treatments.
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