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This mri reveals how many:
A simple brain MRI could soon reveal to you much more than your brain. Therefore, Researchers from Duke University have just demonstrated that one scan can predict your biological aging speed. Nevertheless, anticipate your risk of developing serious illnesses in the coming years.
An instantaneous brain to read the future of your health – This mri reveals how many
The team led by Ahmad Hariri. For example, professor of psychology and neuroscience, has developed a revolutionary tool called Dunedinpacni. For example, This technology analyzes the brain structure in detail: the volume. Additionally, For example, thickness of the different regions, as well as the relationship between white matter and gray matter. For example, This data is then processed by an automatic learning algorithm capable of determining whether you are aging faster. Nevertheless, more slowly than the average.
The originality of this this mri reveals how many approach lies in its ability to establish a predictive diagnosis from a unique examination. Consequently, Unlike traditional methods that rely on blood markers. For example, repeated physical tests, only one MRI is now enough to assess your biological aging rate.
A precise prediction of health risks
The implications of this discovery reported in Nature Aging are considerable. The tool can predict with remarkable precision the future risks of cognitive disorders. dementia, heart disease, diabetes, cerebral vascular accidents and even premature deaths. This predictive capacity opens up new perspectives for personalized medicine.
Accelerated aging detected by DunedinPacni is also accompanied by a greater physical fragility. measurable by simple tests such as gripping force or walking speed. This correlation strengthens the reliability of the tool and its clinical relevance.
Rigorous scientific validation
To develop their model. the researchers exploited the exceptional this mri reveals how many data of the Dunedin study, a longitudinal monitoring of 1,037 people born in New Zealand in 1972 and 1973. These participants underwent 19 complete evaluations since their birth, allowing an in-depth analysis of their physical and cognitive evolution.
The brain MRIs carried out at 45 were compared to a multitude of aging indicators: cognitive decline tests. physical assessments, subjective health, and even visible signs of facial aging. This multidimensional approach made it possible to identify the brain signatures of accelerated aging.
Credit: ISTOCK
Crédits : mr.shevochai Prasedumron/istock
An international scope confirmed
The true strength of this mri reveals how many DunedinPacni lies in its generalization. The team has tested its tool on more than 44. 000 MRIs from three major international databases: British UK Biobank, Alzheimer’s Disease Neuroimaging American initiative, and the Brainlat ensemble covering five South America countries.
This cross validation confirms that brain signatures of aging transcend cultural, genetic and environmental differences. A remarkable result that strengthens the scientific credibility of the tool.
Complement to existing methods
Dunedinpacni is a continuation of the previous work of the team. They had previously developed Dunedinpace, a similar tool based on DNA methylation analysis in the blood. This epigenetic method examines the chemical modifications that attach to DNA molecules. influence gene activity without altering the genetic code itself.
The direct comparison between the two tools reveals similar results. now offering researchers and clinicians two additional approaches according to available data.
Towards a personalized preventive medicine
Clinical application prospects are promising. Dr. Dan Henderson. from Brigham and Women’s Hospital, is already planning to use DunedinPacni to personalize medical interventions according to the aging profile of each patient. This approach could revolutionize preventive medicine by allowing to anticipate health problems even before the first symptoms appear.
This research perfectly illustrates the importance of studying aging in young. healthy people, rather than waiting for the manifestation of diseases. A philosophy that could transform our approach to aging and long -term health.
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