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What every woman should know new: However,
What every woman should know:
Hosted by DRE Margaret Wheeler, a professor emeritus at the University of California in San Francisco and editor associated with JAMA, this episode highlights the latest clinical knowledge on this silent cancer. However, Alongside him. Furthermore. Similarly, the DRS William Cliby (gynecologist-oncologist) and John Weroha (medical oncologist), both experts in the Mayo Clinic in Rochester (Minnesota), decrypt their recently published review in JAMA On the subject.

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Frequent cancer, with misleading symptoms – What every woman should know – What every woman should know new
Ovary cancer is the fifth cause of cancer mortality in women in the United States, and the eighth worldwide. Therefore, Despite a moderate annual impact (around 22. Consequently, 000 cases in the USA), its mortality is very high, comparable to that of pancreatic cancer.
The main fear: its late diagnosis. Moreover, Initial symptoms – abdominal bloating. Nevertheless. early satiety, persistent constipation what every woman should know – are frequent and not very specific, often attributed to banal digestive disorders. Meanwhile, Dr. Consequently. Weroha stresses that many patients are treated for “simple constipation” before an abdominal scanner reveals an already advanced disease: “Knowing the family history of your patients. being attentive to the persistent abdominal symptoms, even trivial, can make all the difference. »»
Ovary cancer screening is still non -existent … – What every woman should know – What every woman should know new
No reliable screening test to date, experts recall. Neither the dosage of CA-125 nor the pelvic ultrasound make it possible to detect the aggressive forms early. It is the persistent symptoms that remain the best indicator.
On the other hand, an in -depth family anamnesis can change the situation. About what every woman should know new 25 % of patients have a genetic or family risk factor, such as a BRCA mutation. In these women. prophylactic surgery (removal of tubes and ovaries) can drastically reduce what every woman should know the risk (from 30–80 % to only 5 %). Dr. Cliby recalls that many patients discover their predisposition after the diagnosis.
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What clinical examinations and imaging in case of ovary cancer?

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Faced with persistent abdominal symptoms. clinicians are invited to perform:
- A pelvic ultrasound,
- A dosage of CA-125 and CEA,
- An attentive what every woman should know new pelvic examination,
- An abdominopelvian scanner in case of doubt,
- An enlarged family history (breast cancers, ovaries, uterus, colon).

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According to specialists, a rapid collaboration with a gynecologist or an what every woman should know oncologist is recommended from the first signs of anomaly in imaging.
Treatments and new therapeutic weapons against this cancer
Treatment is based on surgery (often heavy and extended) and chemotherapy. The objective is the maximum reduction in the tumor mass. called cytoreduction or debulkingassociated with a better prognosis when it is complete and made in an expert center.
In advanced cases, the sequence may vary: neoadjuvant chemotherapy followed by surgery, or vice versa. In the adjuvant phase. all stages, even early, may require chemotherapy in the event of an ovary rupture or microscopic propagation.

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The arrival of Parp inhibitors marked a turning point in care. what every woman should know new especially in patients with BRCA mutation or homologous recombination deficit. These agents make it possible to improve survival significantly.
Another innovation: antibody-drug conjugates (ADC). Dr. Weroha explains the operation of these innovative molecules: “ These what every woman should know are antibodies targeting a tumor receiver. linked to chemotherapy by a linker. This makes it possible to deliver the drug directly to cancer cells, thereby reducing general toxicity. »

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The most recent ADC approved in ovarian cancer – targeting the folic acid receiver – shows a. double response rate compared to standard chemotherapy.
For the first time, More than 50 % of patients with advanced forms are alive at 5 years in the United States. The prognosis depends on many factors: stage, response to surgery, tumor changes, general condition.
But clinicians insist: each patient is unique. A personalized approach, integrating genetics, tumor what every woman should know new biology and access to innovative treatments, is essential.
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